Evidence map›Paper›PMID 29435314›Full record

ArticleUnited European gastroenterology journal2018

Mucosal healing and the risk of serious infections in patients with celiac disease.

Louise Emilsson, Benjamin Lebwohl, Peter Hr Green, Joseph A Murray, Karl Mårild, Jonas F Ludvigsson

Abstract read
In one paragraph

Article in United European gastroenterology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Beyond gluten-free diet: Novel therapeutic frontiers in celiac disease armamentarium.World journal of gastrointestinal pharmacology and therapeutics · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. COVID-19 and celiac disease: a review.Therapeutic advances in gastroenterology · 2023
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Pigment Epithelium-Derived Factor Affects Angiogenesis in Celiac Disease.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2019
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Louise EmilssonDepartment of Health Management and Health Economy, Institute of Health and Society, University of Oslo, Norway.
Benjamin LebwohlDepartment of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Peter Hr GreenDepartment of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Joseph A MurrayDivision of Gastroenterology and Hepatology, Department of Immunology, Mayo Clinic, Rochester, MN, USA.
Karl MårildDivision of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway.
Jonas F LudvigssonDepartment of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Columbia University · USMayo Clinic in Arizona · USUniversity of Colorado Anschutz Medical Campus · USVårdcentralen Teleborg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with celiac disease (CD) are at increased risk of certain infections, but it is unknown if mucosal healing influences this risk.

methodsWe collected data on 29,096 individuals with CD (equal to villous atrophy) through Sweden's 28 pathology departments undergoing biopsy 1969-2008. Through the Swedish Patient Register we obtained information on any infection and specifically sepsis, streptococcal infection, influenza,

resultsOf 5598 CD individuals with no record of any infections before follow-up biopsy, 45% had persistent villous atrophy, 619 (24%) of them had a later infection, compared to 579 (19%) in those with mucosal healing (

conclusionsIn CD, mucosal healing does not influence the risk of serious infection requiring hospital-based medical attention.

Indexed as

Celiac diseaseepidemiologyinfectious disease

Identifiers

PMID29435314
PMCPMC5802675
OpenAlexW2608582524

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.