Evidence map›Paper›PMID 29435268›Full record

ArticleBiomedical reports2018

Common mental disorders and association with telomere length.

E Vakonaki, K Tsiminikaki, S Plaitis, P Fragkiadaki, D Tsoukalas, I Katsikantami, G Vaki, M N Tzatzarakis, D A Spandidos, A M Tsatsakis

Open access · diamondAbstract read
In one paragraph

Article in Biomedical reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 4 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 4 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Association of nutraceutical supplements with longer telomere length.International journal of molecular medicine · 2019
    Trial
  6. Review
  7. Article
  8. The association of depressive symptoms and telomere length among Mexican-origin youth: How it varies by family environment.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Role of telomere length in human carcinogenesis (Review).International journal of oncology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

E VakonakiLaboratory of Toxicology Science and Research, Medical School, University of Crete, 71003 Heraklion, Crete, Greece.
K TsiminikakiLaboratory of Toxicology Science and Research, Medical School, University of Crete, 71003 Heraklion, Crete, Greece.
S PlaitisLaboratory of Toxicology Science and Research, Medical School, University of Crete, 71003 Heraklion, Crete, Greece.
P FragkiadakiLaboratory of Toxicology Science and Research, Medical School, University of Crete, 71003 Heraklion, Crete, Greece.
D TsoukalasLaboratory of Toxicology Science and Research, Medical School, University of Crete, 71003 Heraklion, Crete, Greece.
I KatsikantamiLaboratory of Toxicology Science and Research, Medical School, University of Crete, 71003 Heraklion, Crete, Greece.
G VakiLaboratory of Toxicology Science and Research, Medical School, University of Crete, 71003 Heraklion, Crete, Greece.
M N TzatzarakisLaboratory of Toxicology Science and Research, Medical School, University of Crete, 71003 Heraklion, Crete, Greece.
D A SpandidosLaboratory of Clinical Virology, Medical School, University of Crete, 71409 Heraklion, Crete, Greece.
A M TsatsakisLaboratory of Toxicology Science and Research, Medical School, University of Crete, 71003 Heraklion, Crete, Greece.
University of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Telomeres are repeated 5'-TTAGGG-3' sequences at the end of chromosomes, which maintain genomic stability. Their length is related to a number of diseases that affect humans. Apart from cancer, cardiovascular diseases, diabetes and other, telomere length has been associated with chronic diseases. Chronic mental illness includes various types of mental disorders with the most common being depression, schizophrenia and stress-anxiety. The aim of this review is to summarize the current state of knowledge on the role of telomeres in these disorders and to compare telomere length variations in patients receiving medication and patients not taking treatment. Most studies report reduced telomere length in patients suffering from mental disorders, compared to the general population. Since the factors that can affect telomere length are various, more experiments and investigations are required to understand the general impact of different factors on telomere length.

Indexed as

depressionschizophreniastress-anxietytelomeres

Identifiers

PMID29435268
PMCPMC5778888
OpenAlexW2783761104

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.