Evidence map›Paper›PMID 29435029›Full record

ArticleOncology letters2018

Nucleotide variation in

Jin-Ju Mao, Li-Xiang Wu, Wei Wang, Yuan-Yuan Ye, Jun Yang, Hong Chen, Qian-Fan Yang, Xiu-Yu Zhang, Bo Wang, Wei-Xian Chen

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Pathogenic Single Nucleotide Polymorphisms on Autophagy-Related Genes.International journal of molecular sciences · 2020
    Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jin-Ju MaoDepartment of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 410010, P.R. China.
Li-Xiang WuDepartment of Laboratory Medicine, Chongqing Cancer Institute, Chongqing 400030, P.R. China.
Wei WangDepartment of Laboratory Medicine, Chongqing Cancer Institute, Chongqing 400030, P.R. China.
Yuan-Yuan YeDepartment of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 410010, P.R. China.
Jun YangDepartment of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 410010, P.R. China.
Hong ChenDepartment of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 410010, P.R. China.
Qian-Fan YangDepartment of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 410010, P.R. China.
Xiu-Yu ZhangDepartment of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 410010, P.R. China.
Bo WangDepartment of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 410010, P.R. China.
Wei-Xian ChenDepartment of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 410010, P.R. China.
Second Affiliated Hospital of Chongqing Medical University · CNDalian Medical University · CNChongqing Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early detection of human papillomavirus (HPV) is important for the clinical diagnosis of cervical cancer. However, to date, the pathogenesis of cervical cancer is still unclear. Autophagy is a dynamic process that contributes to the maintenance of cellular homeostasis. Here, we investigate whether variants of autophagy genes affect the occurrence of cervical cancer. In this study, our results indicate that single nucleotide polymorphisms (SNPs) of autophagy-related protein 4 (ATG4), including rs4036579, rs5973822, rs807181, rs807182 and rs807183, have a significant relationship with cervical cancer risk. Furthermore, stratified analysis suggests that the homozygous variant genotype could decrease the risk of cervical cancer and should be considered when investigating the role of HPV in cervical cancer. We aim to investigate whether SNPs of

Indexed as

autophagyautophagy-related protein 4Acervical cancerdonor splice sitehuman papillomavirusSNP

Identifiers

PMID29435029
PMCPMC5778867
OpenAlexW2777768283

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.