Evidence map›Paper›PMID 29434674›Full record

ReviewTherapeutic advances in urology2018

Circulating tumor cells in genitourinary tumors.

Francesco Massari, Vincenzo Di Nunno, Francesca Comito, Marta Cubelli, Chiara Ciccarese, Roberto Iacovelli, Michelangelo Fiorentino, Rodolfo Montironi, Andrea Ardizzoni

Open access · bronzeAbstract readReview
In one paragraph

Review in Therapeutic advances in urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Long Noncoding RNAs as Innovative Urinary Diagnostic Biomarkers.Methods in molecular biology (Clifton, N.J.) · 2021
    Review
  4. Latest progress in molecular biology and treatment in genitourinary tumours.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2020
    Review
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Francesco MassariDivision of Oncology, S.Orsola-Malpighi Hospital, Via Albertoni n.15, Bologna, 40138, Italy.
Vincenzo Di NunnoDivision of Oncology, S.Orsola-Malpighi Hospital, Bologna, Italy.
Francesca ComitoDivision of Oncology, S.Orsola-Malpighi Hospital, Bologna, Italy.
Marta CubelliDivision of Oncology, S.Orsola-Malpighi Hospital, Bologna, Italy.
Chiara CiccareseDepartment of Medical Oncology, Azienda Ospedaliera Universitaria Integrata (AOUI), Verona, Italy.
Roberto IacovelliDepartment of Medical Oncology, Azienda Ospedaliera Universitaria Integrata (AOUI), Verona, Italy.
Michelangelo FiorentinoPathology department, S.Orsola-Malpighi Hospital, Bologna, Italy.
Rodolfo MontironiSection of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy.
Andrea ArdizzoniDivision of Oncology, S.Orsola-Malpighi Hospital, Bologna, Italy.
Policlinico S.Orsola-Malpighi · ITAzienda Ospedaliera Universitaria Integrata Verona · ITMarche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Management of advanced urogenital malignancies has profoundly changed in recent years due to the development of novel targeted drugs that have significantly improved patient's clinical outcomes. This process has been made possible mainly thanks to better knowledge of tumor genetic alterations and molecular altered pathways. Despite these remarkable results, several issues such as early detection of the disease as well as the research into early markers of recurrence or disease progression still remain an open challenge for clinical research. The detection of circulating tumor cells and circulating DNA appears an attractive option since it is a minimally invasive approach potentially able to allow clinicians an accurate diagnosis and maybe lead to more customized treatment strategies. This review focuses on the current techniques adopted for the detection and isolation of circulating tumor cells in genitourinary tumors highlighting their present and possible future application in clinical practice.

Indexed as

biomarkerscirculating tumor cellsearly diagnosisprostate cancerrenal cell carcinomaurothelial cancer

Identifiers

PMID29434674
PMCPMC5805009
OpenAlexW2768277106

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.