Evidence map›Paper›PMID 29434660›Full record

ReviewEcancermedicalscience2018

High-intensity focused ultrasound in the treatment of breast tumours.

Mirjam C L Peek, Feng Wu

Registry-linked trialAbstract readReview
In one paragraph

Review in Ecancermedicalscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07384078 (HIFU vs. CRYO - High Intensity Focused Ultrasound vs. Cryotherapy in the Treatment of Basal Cell Carcinomas and Bowen's Disease - a Randomized Controlled Trial), which is not on this map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07384078 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

HIFU vs. CRYO - High Intensity Focused Ultrasound vs. Cryotherapy in the Treatment of Basal Cell Carcinomas and Bowen's Disease - a Randomized Controlled Trial

TypeinterventionalSponsorJussi SalonenRan2026 to 2032Enrolled294ConditionsSuperficial Basal Cell Carcinoma, Nodular Basal Cell Carcinoma, Bowen's Disease, BCCArmsHigh Intensity Focused Ultrasound, Cryotherapy
3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Review
  3. Imaging in Interventional Radiology: Breast Cryoablation.Seminars in interventional radiology · 2025
    Review
  4. MR Imaging-Guided Focused Ultrasound for Breast Tumors.Magnetic resonance imaging clinics of North America · 2024
    Review
  5. Article
  6. Tissue Ablation: Applications and Perspectives.Advanced materials (Deerfield Beach, Fla.) · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. High intensity focused ultrasound for the treatment of solid tumors: a pilot study in canine cancer patients.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2022
    Article
  13. Article
  14. Time-Resolved Passive Cavitation Mapping Using the Transient Angular Spectrum Approach.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
  15. Review
  16. Article
  17. High-frequency (20 MHz) high-intensity focused ultrasound: New ablative method for color-independent tattoo removal in 1-3 sessions. An open-label exploratory study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2020
    Article
  18. High-frequency (20 MHz) high-intensity focused ultrasound: New Treatment of actinic keratosis, basal cell carcinoma, and Kaposi sarcoma. An open-label exploratory study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2020
    Article
  19. Review
  20. Photodynamic Therapy in Primary Breast Cancer.Journal of clinical medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mirjam C L PeekResearch Oncology, Division of Cancer Studies, King's College London, Guy's Hospital Campus, Great Maze Pond, London SE1 9RT, UK.
Feng WuHIFU Unit, The Churchill Hospital, Oxford University Hospitals, Headington, Oxford OX3 7LJ, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-intensity focused ultrasound (HIFU) is a minimally invasive technique that has been used for the treatment of both benign and malignant tumours. With HIFU, an ultrasound (US) beam propagates through soft tissue as a high-frequency pressure wave. The US beam is focused at a small target volume, and due to the energy building up at this site, the temperature rises, causing coagulative necrosis and protein denaturation within a few seconds. HIFU is capable of providing a completely non-invasive treatment without causing damage to the directly adjacent tissues. HIFU can be either guided by US or magnetic resonance imaging (MRI). Guided imaging is used to plan the treatment, detect any movement during the treatment and monitor response in real-time. This review describes the history of HIFU, the HIFU technique, available devices and gives an overview of the published literature in the treatment of benign and malignant breast tumours with HIFU.

Indexed as

breast cancerhigh-intensity focused ultrasound (HIFU)

Identifiers

PMID29434660
PMCPMC5804717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.