Evidence map›Paper›PMID 29434523›Full record

ArticleClinical and molecular allergy : CMA2018

Allergic sensitization to common pets (cats/dogs) according to different possible modalities of exposure: an Italian Multicenter Study.

G Liccardi, L Calzetta, G Baldi, A Berra, L Billeri, M Caminati, P Capano, E Carpentieri, A Ciccarelli, M A Crivellaro and 31 more

Abstract read
In one paragraph

Article in Clinical and molecular allergy : CMA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Representative Nasal Endoscopic Findings Suggestive of Allergic Rhinitis and Their Influencing Factors.Journal of rhinology : official journal of the Korean Rhinologic Society · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Sensitization to molecular dog allergens in an adult population: Results from the West Sweden Asthma Study.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2023
    Article
  7. Review
  8. Article
  9. Bedroom Allergen Exposure Beyond House Dust Mites.Current allergy and asthma reports · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors.

G Liccardi1Department of Pulmonology, Haematology and Oncology. Division of Pneumology and Allergology, High Speciality "A. Cardarelli" Hospital, Naples, Italy.
L Calzetta2Postgraduate School of Respiratory Medicine. Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", Rome, Italy.
G BaldiRespiratory Medicine Unit, ASL (District 66), Salerno, Italy.
A BerraRespiratory Allergy Unit, G. Da Procida Hospital, Salerno, Italy.
L Billeri6Department of Laboratory Medicine, University Hospital Padova, Padua, Italy.
M Caminati7Asthma Center and Allergy Unit, Verona University and General Hospital, Verona, Italy.
P CapanoUnit of Pulmonary Immunology and Respiratory Diseases Ospedale "Santa Maria Della Speranza", Battipaglia, Salerno Italy.
E CarpentieriDivision of Pneumology, "Santa Maria Novella" Hospital, Galatina, Lecce Italy.
A CiccarelliAllergy Unit, Loreto Crispi Hospital, Naples, Italy.
M A Crivellaro11Unit of Allergy and Occupational Medicine, University Hospital Padova, Padua, Italy.
M CutajarAllergy Center, Division of Internal Medicine, Ospedali Riuniti Penisola Sorrentina, Sorrento, Naples, Italy.
M D'Amato13Department of Respiratory Disease, "Federico II" University - AO "Dei Colli", Naples, Italy.
I Folletti14Department of Medicine, Section of Occupational Medicine, Respiratory Diseases and Toxicology, Terni Hospital, University of Perugia, Perugia, Italy.
F GaniAllergy Unit, S. Luigi Gonzaga Hospital, Orbassano, Turin, Italy.
D Gargano16Allergy Unit, High Speciality "San Giuseppe Moscati" Hospital, Avellino, Italy.
D GiannattasioRespiratory Physiopathology and Allergy, High Speciality Center, "Mauro Scarlato" Hospital, Scafati, Salerno, Italy.
M GiovanniniPulmonary Diseases Department, Mirandola Hospital, Modena, Italy.
C Lombardi19Departmental Unit of Allergy, Clinical Immunology and Respiratory Diseases, Fondazione Poliambulanza, Brescia, Italy.
M Lo SchiavoAllergy and Clinical Immunology, "G. Fucito" Hospital, S. Giovanni di Dio e Ruggi D'Aragona University Hospital, Salerno, Italy.
F MadonnaAllergy Unit, ASL (Sanitary District n°12), Caserta, Italy.
M ManiscalcoPulmonary Rehabilitation Unit, ICS Maugeri, Telese Terme, Benevento Italy.
A Meriggi23Allergy and Immunology Unit, Fondazione "Salvatore Maugeri", Institut of Research and Care, Scientific Institute of Pavia, Pavia, Italy.
C MicucciDivision of Pneumology and Allergology Hospital "Carlo Urbani", Jesi, Ancona Italy.
M Milanese25Division of Pneumology, S. Corona Hospital, Pietra Ligure, Savona Italy.
C MonteraAllergy and Clinical Immunology, "G. Fucito" Hospital, S. Giovanni di Dio e Ruggi D'Aragona University Hospital, Salerno, Italy.
G Paolocci14Department of Medicine, Section of Occupational Medicine, Respiratory Diseases and Toxicology, Terni Hospital, University of Perugia, Perugia, Italy.
R Parente26Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy.
A Pedicini27Division of Internal Medicine and Allergy, Fatebenefratelli Hospital, Benevento, Italy.
R PioAllergy and Clinical Immunology, "G. Fucito" Hospital, S. Giovanni di Dio e Ruggi D'Aragona University Hospital, Salerno, Italy.
F PuggioniRespiratory Diseases Department-IRCCS Humanitas Research and Clinical Center, Rozzano, Milan, Italy.
M Russo1Department of Pulmonology, Haematology and Oncology. Division of Pneumology and Allergology, High Speciality "A. Cardarelli" Hospital, Naples, Italy.
A Salzillo1Department of Pulmonology, Haematology and Oncology. Division of Pneumology and Allergology, High Speciality "A. Cardarelli" Hospital, Naples, Italy.
P ScavalliUnit of Respiratory Physiopathology, Allergy and Occupational Medicine, ASL Viterbo, Viterbo, Italy.
N Scichilone30Biomedical Department of Specialistic and Internal Medicine, University of Palermo, Palermo, Italy.
B SposatoPneumology Unit, Azienda Ospedaliera "Misericordia", Grosseto, Italy.
A Stanziola13Department of Respiratory Disease, "Federico II" University - AO "Dei Colli", Naples, Italy.
G Steinhilber32Division of Pneumology, Spedali Civili Brescia, Brescia, Italy.
A Vatrella33Department of Medicine and Surgery, University of Salerno, Fisciano, Italy.
P Rogliani2Postgraduate School of Respiratory Medicine. Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", Rome, Italy.
G Passalacqua34Allergy and Respiratory Diseases, Policlinico San Martino, University of Genoa, Genoa, Italy.
Italian Allergic Respiratory Diseases Task Force

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe query "are there animals at home?" is usually administered for collecting information on anamnesis. This modality to consider exposure to pet allergens constitutes a potential bias in epidemiological studies and in clinical practice. The aim of our study was to evaluate/quantify different modalities of exposure to cat/dog in inducing allergic sensitization.

methodsThirty Italian Allergy units participated in this study. Each centre was required to collect the data of at least 20 consecutive outpatients sensitized to cat/dog allergens. A standardized form reported all demographic data and a particular attention was paid in relieving possible modalities of exposure to cat/dog.

resultsA total 723 patients sensitized to cat/dog were recorded, 359 (49.65%) reported direct pet contact, 213 patients (29.46%) were pet owners, and 146 subjects (20.19%) were exposed to pets in other settings. Other patients were sensitized by previous pet ownership (150-20.75%) or indirect contact (103-14.25%), in 111 subjects (15.35%) any contact was reported.

conclusionsOnly 213 patients (29.46%) would be classified as "exposed to animals" and 510 (70.54%) as "not exposed" according to usual query. Our classification has shown that many "not-exposed" subjects (399-55.19%) were "really exposed". The magnitude of exposure to pet allergens at home is not related exclusively to pet ownership. These considerations should be taken into account during the planning of epidemiological studies and in clinical practice for the management of pet allergic individuals.

Indexed as

Allergic rhinitisAllergic sensitizationBronchial asthmaCatDogHypersensitivityPetsPets exposure

Identifiers

PMID29434523
PMCPMC5796344

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