ReviewNature reviews. Urology2018
Bladder biomechanics and the use of scaffolds for regenerative medicine in the urinary bladder.
Review in Nature reviews. Urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Review of clinical experience on biomaterials and tissue engineering of urinary bladder.World journal of urology · 2020Pooled it
- Biomechanical regulation of bladder injury and repair.Nature reviews. Urology · 2026Review
- The engineered bladder patch with a three-layer structure promotes the regeneration and functional recovery of the bladder in a rabbit model.Bioengineering & translational medicine · 2026Article
- Transformative biomechanics and mechanobiology breakthroughs shaping the future of health and medicine.Innovation (Cambridge (Mass.)) · 2026Review
- Single-staged in vivo co-transplantation of autologous muscular and urothelial micrografts as a composite tissue tube for urogenital reconstruction.Pediatric surgery international · 2026Article
- Bladder Defect Repair by Polycaprolactone/Gelatin Nanofiber Scaffolds Loaded with Mitomycin Through Anti-Fibrotic Effects.International journal of nanomedicine · 2026Article
- Biomimetic, Suturable, and Extensible Electrospun Scaffolds for Lower Urinary Tract Surgical Reconstruction.Advanced healthcare materials · 2025Article
- Development of a Decellularized Urinary Bladder Matrix and Heparin-Based Cryogel for Promoting Angiogenesis.Macromolecular bioscience · 2025Article
- Development of anMatrix biology plus · 2025Article
- The BAM-GelMA-ADSCs bilayer patch promotes tissue regeneration and functional recovery after large-area bladder defects in beagles.Bioengineering & translational medicine · 2025Article
- Recent advances and future directions in urinary system tissue engineering.Materials today. Bio · 2025Review
- Stem Cell Therapies in Canine Cardiology: Comparative Efficacy, Emerging Trends, and Clinical Integration.Biomolecules · 2025Review
- Electrospinning strategies targeting fibroblast for wound healing of diabetic foot ulcers.APL bioengineering · 2025Review
- Enhanced Bladder Regeneration with Adipose-Derived Stem Cell-Seeded Silk Fibroin Scaffolds: A Comparative Analysis.Biomimetics (Basel, Switzerland) · 2025Article
- Cell-free biodegradable electroactive scaffold for urinary bladder tissue regeneration.Nature communications · 2025Article
- [Application and progress of bio-derived materials in bladder regeneration and repair].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024Review
- Autologous micrografting improves regeneration of tissue-engineered urinary conduits in vivo.Scientific reports · 2024Article
- Article
- Recent advances in innovative biomaterials for promoting bladder regeneration: processing and functionalization.Frontiers in bioengineering and biotechnology · 2024Review
- Advancing autologous urothelial micrografting and composite tubular grafts for future single-staged urogenital reconstructions.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The urinary bladder is a complex organ with the primary functions of storing urine under low and stable pressure and micturition. Many clinical conditions can cause poor bladder compliance, reduced capacity, and incontinence, requiring bladder augmentation or use of regenerative techniques and scaffolds. To replicate an organ that is under frequent mechanical loading and unloading, special attention towards fulfilling its biomechanical requirements is necessary. Several biological and synthetic scaffolds are available, with various characteristics that qualify them for use in bladder regeneration in vitro and in vivo, including in the treatment of clinical conditions. The biomechanical properties of the native bladder can be investigated using a range of mechanical tests for standardized assessments, as well as mathematical and computational bladder biomechanics. Despite a large body of research into tissue engineering of the bladder wall, some features of the native bladder and the scaffolds used to mimic it need further elucidation. Collection of comparable reference data from different animal models would be a helpful tool for researchers and will enable comparison of different scaffolds in order to optimize characteristics before entering preclinical and clinical trials.
Indexed as
Identifiers
29434369What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.