ArticleScientific reports2018
Vaccination Against Lawsonia intracellularis Decreases Shedding of Salmonella enterica serovar Typhimurium in Co-Infected Pigs and Alters the Gut Microbiome.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 44 citations in OpenAlex.
- Examination ofVeterinary and animal science · 2026Article
- The Lawsonia Paradox: The Hidden Burden of Silent Disease.Pathogens (Basel, Switzerland) · 2026Review
- Lawsonia intracellularis infection induces changes in microbial community function and composition associated with reduced pig growth and feed efficiency.Animal microbiome · 2026Article
- Prevalence ofFrontiers in microbiology · 2026Article
- Oral fluids for detection and characterization ofFrontiers in veterinary science · 2026Article
- Article
- Article
- Development and validation of a flow cytometry antibody test forFrontiers in immunology · 2023Article
- Serological Assessment ofPathogens (Basel, Switzerland) · 2022Article
- A framework for testing the impact of co-infections on host gut microbiomes.Animal microbiome · 2022Review
- Sow vaccination against virulent Glaesserella parasuis shapes the nasal microbiota of their offspring.Scientific reports · 2022Article
- Microbiota of vaccinated and non-vaccinated clinically inconspicuous and conspicuous piglets under naturalFrontiers in veterinary science · 2022Article
- A Systematic Review on the Effectiveness of Pre-Harvest Meat Safety Interventions in Pig Herds to ControlMicroorganisms · 2021Review
- Oral Vaccination againstAnimals : an open access journal from MDPI · 2021Article
- Lawsonia intracellularis infected enterocytes lack sucrase-isomaltase which contributes to reduced pig digestive capacity.Veterinary research · 2021Article
- Reduction ofHeliyon · 2021Article
- Probiotics mediated gut microbiota diversity shifts are associated with reduction in histopathology and shedding of Lawsonia intracellularis.Animal microbiome · 2021Article
- Relationships among Fecal, Air, Oral, and Tracheal Microbial Communities in Pigs in a Respiratory Infection Disease Model.Microorganisms · 2021Article
- Oral Vaccination Reduces the Effects ofFrontiers in veterinary science · 2021Article
- Bacillus pumilus probiotic feed supplementation mitigates Lawsonia intracellularis shedding and lesions.Veterinary research · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Salmonella enterica serovar Typhimurium continues to be a major cause of foodborne illness worldwide and pork can serve as a source of infection. Co-infection of S. enterica with Lawsonia intracellularis, a common intestinal pathogen of swine, has been found as risk factor for increased S. enterica shedding. The objective of this study was to investigate if vaccination against L. intracellularis could lead to decreased S. Typhimurium shedding. To test this hypothesis, pigs were challenged with either S. Typhimurium or S. Typhimurium and L. intracellularis, with and without L. intracellularis vaccination (n = 9 per group). A non-challenged group served as a negative control. Vaccination decreased the shedding of S. Typhimurium in co-infected animals by 2.12 log
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.