Evidence map›Paper›PMID 29434164›Full record

ArticleInternal medicine (Tokyo, Japan)2018

Nivolumab Induces Sustained Liver Injury in a Patient with Malignant Melanoma.

Tokuhiro Matsubara, Tsutomu Nishida, Yu Higaki, Ryo Tomita, Hiromi Shimakoshi, Akiyoshi Shimoda, Naoto Osugi, Aya Sugimoto, Kei Takahashi, Dai Nakamatsu and 5 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

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  8. Morphology of tumor and nontumor tissue in liver resection specimens for hepatocellular carcinoma following nivolumab therapy.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021
    Article
  9. Review
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  11. Hepatobiliary and Pancreatic Adverse Events.Advances in experimental medicine and biology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Tokuhiro MatsubaraDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Tsutomu NishidaDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Yu HigakiDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Ryo TomitaDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Hiromi ShimakoshiDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Akiyoshi ShimodaDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Naoto OsugiDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Aya SugimotoDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Kei TakahashiDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Dai NakamatsuDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Kaori MukaiDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Masashi YamamotoDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Koji FukuiDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Shiro AdachiDepartment of Pathology, Toyonaka Municipal Hospital, Japan.
Masami InadaDepartment of Gastroenterology, Toyonaka Municipal Hospital, Japan.
Toyonaka Municipal Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 42-year-old man was diagnosed with cStage IIIb malignant melanoma and underwent resection. After interferon-beta therapy, 18-fluorodeoxyglucose-positron emission tomography/computed tomography (

Indexed as

AdultAntibodies, MonoclonalBone NeoplasmsChemical and Drug Induced Liver InjuryFluorodeoxyglucose F18HumansInterferon-betaLiverLung NeoplasmsMaleMelanomaNivolumabPositron-Emission TomographyPositron Emission Tomography Computed TomographyTomography, X-Ray ComputedAntibodies, MonoclonalFluorodeoxyglucose F18Interferon-betaNivolumabimmune checkpoint inhibitorsimmune-related adverse eventsnivolumabpersistent liver injury

Identifiers

PMID29434164
PMCPMC6047996
OpenAlexW2785540177

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.