Evidence map›Paper›PMID 29434152›Full record

ArticleInternal medicine (Tokyo, Japan)2018

Whipple's Disease with Long-term Endoscopic Follow-up.

Hiroaki Saito, Junji Shiode, Shogen Ohya, Atsushi Yao, Shunsuke Saito, Masakuni Fujii, Mamoru Itoh, Shuhei Ishiyama, Akiko Fujiwara, Junichiro Nasu and 2 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Whipple's disease? A case report and discussion.Medicine and pharmacy reports · 2021
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Hiroaki SaitoDepartment of Internal Medicine, Okayama Saiseikai General Hospital, Japan.
Junji ShiodeDepartment of Internal Medicine, Okayama Saiseikai General Hospital, Japan.
Shogen OhyaDepartment of Internal Medicine, Okayama Saiseikai General Hospital, Japan.
Atsushi YaoDepartment of Internal Medicine (Nephrology), Kanto Rosai Hospital, Japan.
Shunsuke SaitoDepartment of Internal Medicine, Okayama Saiseikai General Hospital, Japan.
Masakuni FujiiDepartment of Internal Medicine, Okayama Saiseikai General Hospital, Japan.
Mamoru ItohDepartment of Internal Medicine, Okayama Saiseikai General Hospital, Japan.
Shuhei IshiyamaDepartment of Internal Medicine, Okayama Saiseikai General Hospital, Japan.
Akiko FujiwaraDepartment of Internal Medicine, Okayama Saiseikai General Hospital, Japan.
Junichiro NasuDepartment of Internal Medicine, Okayama Saiseikai General Hospital, Japan.
Masao YoshiokaDepartment of Internal Medicine, Okayama Saiseikai General Hospital, Japan.
Kazuhide YamamotoDepartment of Internal Medicine, Okayama Saiseikai General Hospital, Japan.
Okayama Saiseikai General Hospital · JPNoguchi Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 72-year-old man presented with anorexia and 15-kg weight loss over 3 years. Endoscopy revealed yellow, shaggy mucosa alternating with erythematous, eroded mucosa in the duodenum. Biopsy specimens showed massive infiltration of periodic acid-Schiff-positive macrophages in the lamina propria, consistent with Whipple's disease. The patient was treated with intravenous ceftriaxone for four weeks, followed by oral trimethoprim-sulfamethoxazole. His condition improved, and he gradually gained weight. Although the endoscopic findings improved with continuous trimethoprim-sulfamethoxazole administration, macrophage infiltration of the duodenal mucosa persisted. However, the patient has been symptom-free for eight years.

Indexed as

AgedAnti-Bacterial AgentsCeftriaxoneDuodenumEndoscopyFollow-Up StudiesHumansIntestinal MucosaMacrophagesMaleTrimethoprim, Sulfamethoxazole Drug CombinationWhipple DiseaseAnti-Bacterial AgentsCeftriaxoneTrimethoprim, Sulfamethoxazole Drug CombinationendoscopymacrophageTropheryma whippleiWhipple's disease

Identifiers

PMID29434152
PMCPMC6047986
OpenAlexW2792025568

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.