Evidence map›Paper›PMID 29434052›Full record

ArticleThe Journal of pharmacology and experimental therapeutics2018

In Vitro and In Vivo Antitumor and Anti-Inflammatory Capabilities of the Novel GSK3 and CDK9 Inhibitor ABC1183.

Randy S Schrecengost, Cecelia L Green, Yan Zhuang, Staci N Keller, Ryan A Smith, Lynn W Maines, Charles D Smith

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of pharmacology and experimental therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Observational
  2. Article
  3. Review
  4. P-TEFb as A Promising Therapeutic Target.Molecules (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Randy S SchrecengostApogee Biotechnology Corporation, Hummelstown, Pennsylvania.
Cecelia L GreenApogee Biotechnology Corporation, Hummelstown, Pennsylvania.
Yan ZhuangApogee Biotechnology Corporation, Hummelstown, Pennsylvania.
Staci N KellerApogee Biotechnology Corporation, Hummelstown, Pennsylvania.
Ryan A SmithApogee Biotechnology Corporation, Hummelstown, Pennsylvania.
Lynn W MainesApogee Biotechnology Corporation, Hummelstown, Pennsylvania.
Charles D SmithApogee Biotechnology Corporation, Hummelstown, Pennsylvania cdsmith@apogee-biotech.com.
Apogee Biotechnology (United States) · US

Funding

Project 3: Targeting SK2/S1P Signaling for the Regulation of c-Myc and Tumor SuppressionP01CA203628 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BIELAWSKA, ALICJA · 2016 to 2021
$8.9M
NCI NIH HHS P01 CA203628
6 · The paper itself

Abstract

Glycogen synthase kinase-3s (GSK3

Indexed as

Anti-Inflammatory AgentsAntineoplastic AgentsCyclin-Dependent Kinase 9Glycogen Synthase Kinase 3HumansInflammatory Bowel DiseasesNitrilesProtein Kinase InhibitorsAnti-Inflammatory AgentsAntineoplastic AgentsbenzonitrileCyclin-Dependent Kinase 9Glycogen Synthase Kinase 3NitrilesProtein Kinase Inhibitors

Identifiers

PMID29434052
PMCPMC5830635
OpenAlexW2793625085

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.