Evidence map›Paper›PMID 29434032›Full record

ArticleG3 (Bethesda, Md.)2018

Selection on Expected Maximum Haploid Breeding Values Can Increase Genetic Gain in Recurrent Genomic Selection.

Dominik Müller, Pascal Schopp, Albrecht E Melchinger

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. A Similarity Matrix for Preserving Haplotype Diversity Amongst Parents in Genomic Selection.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2025
    Article
  5. Haplotype stacking to improve stability of stripe rust resistance in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  6. Practical Considerations When Using Mendelian Sampling Variances for Selection Decisions in Genomic Selection Programs.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Stacking beneficial haplotypes from the Vavilov wheat collection to accelerate breeding for multiple disease resistance.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024
    Article
  12. Article
  13. Article
  14. Genome-wide atlas of rust resistance loci in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Genomic prediction in hybrid breeding: II. Reciprocal recurrent genomic selection with full-sib and half-sib families.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dominik MüllerUniversity of Hohenheim, Institute of Plant Breeding, Seed Science and Population Genetics, Fruhwirthstr. 21, 70599 Stuttgart and.
Pascal SchoppKWS SAAT SE, Grimsehlstraβe 31, 37574 Einbeck.
Albrecht E MelchingerUniversity of Hohenheim, Institute of Plant Breeding, Seed Science and Population Genetics, Fruhwirthstr. 21, 70599 Stuttgart and melchinger@uni-hohenheim.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genomic selection (GS) offers the possibility to estimate the effects of genome-wide molecular markers, which can be used to calculate genomic estimated breeding values (GEBVs) for individuals without phenotypes. GEBVs can serve as a selection criterion in recurrent GS, maximizing single-cycle but not necessarily long-term genetic gain. As simple genome-wide sums, GEBVs do not take into account other genomic information, such as the map positions of loci and linkage phases of alleles. Therefore, we herein propose a novel selection criterion called expected maximum haploid breeding value (EMBV). EMBV predicts the expected performance of the best among a limited number of gametes that a candidate contributes to the next generation, if selected. We used simulations to examine the performance of EMBV in comparison with GEBV as well as the recently proposed criterion optimal haploid value (OHV) and weighted GS. We considered different population sizes, numbers of selected candidates, chromosome numbers and levels of dominant gene action. Criterion EMBV outperformed GEBV after about 5 selection cycles, achieved higher long-term genetic gain and maintained higher diversity in the population. The other selection criteria showed the potential to surpass both GEBV and EMBV in advanced cycles of the breeding program, but yielded substantially lower genetic gain in early to intermediate cycles, which makes them unattractive for practical breeding. Moreover, they were largely inferior in scenarios with dominant gene action. Overall, EMBV shows high potential to be a promising alternative selection criterion to GEBV for recurrent genomic selection.

Indexed as

BreedingGenomicsHaploidySelection, GeneticComputer SimulationGenetic VariationHeterozygotedoubled haploidexpected maximum haploid breeding valuegenetic gainGenomic SelectionGenPredoptimal haploid valueShared Data Resources

Identifiers

PMID29434032
PMCPMC5873908

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.