Evidence map›Paper›PMID 29433556›Full record

ArticleWorld journal of surgical oncology2018

Treatment of glioblastoma with herbal medicines.

Ivo Trogrlić, Dragan Trogrlić, Darko Trogrlić, Amina Kadrić Trogrlić

Open access · goldAbstract read
In one paragraph

Article in World journal of surgical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Journal of biomedical physics & engineering · 2026
    Article
  2. Review
  3. Article
  4. Anticancer Activity of Aaptos suberitoides on Glioblastoma Multiforme Cell Line.Asian Pacific journal of cancer prevention : APJCP · 2024
    Article
  5. Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ivo TrogrlićFamily business "DREN" Ltd, Žepče, Bosnia and Herzegovina.
Dragan TrogrlićFamily business "DREN" Ltd, Žepče, Bosnia and Herzegovina. dragan.trogrlic@tel.net.ba.ORCID http://orcid.org/0000-0002-4363-7103
Darko TrogrlićFamily business "DREN" Ltd, Žepče, Bosnia and Herzegovina.
Amina Kadrić TrogrlićFamily business "DREN" Ltd, Žepče, Bosnia and Herzegovina.
Dollezhal Research and Development Institute of Power Engineering · RUUniversity of Zenica · BA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the latest years, a lot of research studies regarding the usage of active agents from plants in the treatment of tumors have been published, but there is no data about successful usage of herbal remedies in the treatment of glioblastoma in humans.

methodsThe phytotherapy involved five types of herbal medicine which the subjects took in the form of tea, each type once a day at regular intervals. Three patients took herbal medicine along with standard oncological treatment, while two patients applied for phytotherapy after completing medical treatment. The composition of herbal medicine was modified when necessary, which depended on the results of the control scans using the nuclear magnetic resonance technique and/or computed tomography.

resultsForty-eight months after the introduction of phytotherapy, there were no clinical or radiological signs of the disease, in three patients; in one patient, the tumor was reduced and his condition was stable, and one patient lived for 48 months in spite of a large primary tumor and a massive recurrence, which developed after the treatment had been completed.

conclusionsThe results achieved in patients in whom tumor regression occurred exclusively through the use of phytotherapy deserve special attention. In order to treat glioblastoma more effectively, it is necessary to develop innovative therapeutic strategies and medicines that should not be limited only to the field of conventional medicine. The results presented in this research paper are encouraging and serve as a good basis for further research on the possibilities of phytotherapy in the treatment of glioblastoma.

Indexed as

Herbal MedicineAdolescentAdultAntineoplastic AgentsFemaleFollow-Up StudiesGlioblastomaHumansMaleMiddle AgedPhytotherapyPlants, MedicinalPrognosisSurvival RateAntineoplastic AgentsComputed tomographyGlioblastomaNuclear magnetic resonancePhytotherapyRecurrence

Identifiers

PMID29433556
PMCPMC5809810
OpenAlexW2803559522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.