ArticleBMC plant biology2018
Sequence variation and functional analysis of a FRIGIDA orthologue (BnaA3.FRI) in Brassica napus.
Article in BMC plant biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 35 citations in OpenAlex.
- A functional FRIa variant drives turnip adaptation to the Qinghai-Xizang Plateau.Molecular horticulture · 2026Article
- Article
- Transposon insertions within alleles of BnaFT.A2 are associated with seasonal crop type in rapeseed.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Machine learning assisted dynamic phenotypes and genomic variants help understand the ecotype divergence in rapeseed.Frontiers in plant science · 2022Article
- Functional homoeologous alleles of CONSTANS contribute to seasonal crop type in rapeseed.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Comparative transcriptome analysis and identification of candidate adaptive evolution genes ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- QTL-seq identifies BnaFT.A02 and BnaFLC.A02 as candidates for variation in vernalization requirement and response in winter oilseed rape (Brassica napus).Plant biotechnology journal · 2020Article
- The ubiquitin system affects agronomic plant traits.The Journal of biological chemistry · 2020Review
- Genome Triplication Leads to Transcriptional Divergence ofFrontiers in plant science · 2020Review
- Eight high-quality genomes reveal pan-genome architecture and ecotype differentiation of Brassica napus.Nature plants · 2020Article
- GWAS hints at pleiotropic roles for FLOWERING LOCUS T in flowering time and yield-related traits in canola.BMC genomics · 2019Article
- Identification and characterization of a new dwarf locus DS-4 encoding an Aux/IAA7 protein in Brassica napus.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
- Translating Flowering Time From Arabidopsis thaliana to Brassicaceae and Asteraceae Crop Species.Plants (Basel, Switzerland) · 2018Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundAllelic variation at the FRIGIDA (FRI) locus is a major contributor to natural variation of flowering time and vernalization requirement in Arabidopsis thaliana. Dominant FRI inhibits flowering by activating the expression of the MADS box transcriptional repressor FLOWERING LOCUS C (FLC), which represses flowering prior to vernalization. Four FRI orthologues had been identified in the domesticated amphidiploid Brassica napus. Linkage and association studies had revealed that one of the FRI orthologues, BnaA3.FRI, contributes to flowering time variation and crop type differentiation.
resultsSequence analyses indicated that three out of the four BnaFRI paralogues, BnaA3.FRI, BnaA10.FRI and BnaC3.FRI, contained a large number of polymorphic sites. Haplotype analysis in a panel of 174 B. napus accessions using PCR markers showed that all the three paralogues had a biased distribution of haplotypes in winter type oilseed rape (P < 0.01). Association analysis indicated that only BnaA3.FRI contributes to flowering time variation in B. napus. In addition, transgenic functional complementation demonstrated that mutations in the coding sequence of BnaA3.FRI lead to weak alleles, and subsequently to flowering time variation.
conclusionThis study for the first time provides a molecular basis for flowering time control by BnaA3.FRI in B. napus, and will facilitate predictive oilseed rape breeding to select varieties with favorable flowering time and better adaption to latitude and seasonal shifts due to changing climate.
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