Evidence map›Paper›PMID 29432191›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Divergent and parallel routes of biochemical adaptation in high-altitude passerine birds from the Qinghai-Tibet Plateau.

Xiaojia Zhu, Yuyan Guan, Anthony V Signore, Chandrasekhar Natarajan, Shane G DuBay, Yalin Cheng, Naijian Han, Gang Song, Yanhua Qu, Hideaki Moriyama and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 121 citations in OpenAlex.

  1. Article
  2. The genetic foundations of convergent traits.Nature reviews. Genetics · 2026
    Review
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  8. Convergent High OAnimals : an open access journal from MDPI · 2024
    Article
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  14. Mutation bias and the predictability of evolution.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Xiaojia ZhuKey Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, 100101 Beijing, China.
Yuyan GuanKey Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, 100101 Beijing, China.
Anthony V SignoreSchool of Biological Sciences, University of Nebraska, Lincoln, NE 68588.
Chandrasekhar NatarajanSchool of Biological Sciences, University of Nebraska, Lincoln, NE 68588.ORCID 0000-0002-4841-0426
Shane G DuBayCommittee on Evolutionary Biology, University of Chicago, Chicago, IL 60637.
Yalin ChengKey Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, 100101 Beijing, China.
Naijian HanKey Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, 100101 Beijing, China.
Gang SongKey Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, 100101 Beijing, China.
Yanhua QuKey Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, 100101 Beijing, China.
Hideaki MoriyamaSchool of Biological Sciences, University of Nebraska, Lincoln, NE 68588.
Federico G HoffmannDepartment of Biochemistry, Molecular Biology, Entomology, and Plant Pathology, Mississippi State University, Mississippi State, MS 39762.
Angela FagoDepartment of Bioscience, Aarhus University, DK-8000 Aarhus, Denmark.
Fumin LeiKey Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, 100101 Beijing, China; leifm@ioz.ac.cn jstorz2@unl.edu.
Jay F StorzSchool of Biological Sciences, University of Nebraska, Lincoln, NE 68588; leifm@ioz.ac.cn jstorz2@unl.edu.ORCID 0000-0001-5448-7924
Chinese Academy of Sciences · CNUniversity of Nebraska–Lincoln · USAarhus University · DKField Museum of Natural History · USMississippi State University · US

Funding

Mutational Pleiotropy, Epistasis, and the Adaptive Evolution of Hemoglobin FunctionR01HL087216 · NHLBI · UNIVERSITY OF NEBRASKA LINCOLN · PI STORZ, JAY · 2008 to 2021
$4.5M
NHLBI NIH HHS R01 HL087216
6 · The paper itself

Abstract

When different species experience similar selection pressures, the probability of evolving similar adaptive solutions may be influenced by legacies of evolutionary history, such as lineage-specific changes in genetic background. Here we test for adaptive convergence in hemoglobin (Hb) function among high-altitude passerine birds that are native to the Qinghai-Tibet Plateau, and we examine whether convergent increases in Hb-O

Indexed as

AltitudeAdaptation, PhysiologicalAnimal DistributionAnimalsEvolution, MolecularHemoglobinsModels, MolecularPasseriformesProtein ConformationProtein IsoformsTibetHemoglobinsProtein Isoformsbiochemical adaptationconvergencehemoglobinhypoxiamutation bias

Identifiers

PMID29432191
PMCPMC5828625
OpenAlexW2789393752

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.