Evidence map›Paper›PMID 29432148›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Sandeep Chhabra, Patrick Fischer, Koh Takeuchi, Abhinav Dubey, Joshua J Ziarek, Andras Boeszoermenyi, Daniel Mathieu, Wolfgang Bermel, Norman E Davey, Gerhard Wagner and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 45 citations in OpenAlex.

  1. Journal of biomolecular NMR · 2025
    Article
  2. How does NFAT3 regulate the occurrence of cardiac hypertrophy?International journal of cardiology. Heart & vasculature · 2023
    Review
  3. Article
  4. Article
  5. Chemical communications (Cambridge, England) · 2022
    Article
  6. SelectiveAngewandte Chemie (International ed. in English) · 2022
    Article
  7. Article
  8. NMR illuminates intrinsic disorder.Current opinion in structural biology · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

Sandeep ChhabraDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.
Patrick FischerDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.
Koh TakeuchiMolecular Profiling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology, 135-0064 Tokyo, Japan.
Abhinav DubeyDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.
Joshua J ZiarekDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.
Andras BoeszoermenyiDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.
Daniel MathieuMagnetic Resonance Spectroscopy NMR Application, Bruker BioSpin GmbH, 76287 Rheinstetten, Germany.
Wolfgang BermelMagnetic Resonance Spectroscopy NMR Application, Bruker BioSpin GmbH, 76287 Rheinstetten, Germany.
Norman E DaveyConway Institute of Biomolecular and Biomedical Sciences, University College Dublin, Dublin 4, Ireland.
Gerhard WagnerDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115; gerhard_wagner@hms.harvard.edu hari@hms.harvard.edu.
Haribabu ArthanariDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115; gerhard_wagner@hms.harvard.edu hari@hms.harvard.edu.
Harvard University · USBruker (Germany) · DEDana-Farber Cancer Institute · USIndiana University Bloomington · USNational Institute of Advanced Industrial Science and Technology · JPUniversity College Dublin · IE

Funding

T CELL SPECIFIC TRANSCRIPTION COMPLEXESP01GM047467 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WAGNER, GERHARD · 1992 to 2017
$28.6M
OverallP41EB002026 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GRIFFIN, ROBERT GUY · 2003 to 2018
$17.9M
Roles of Eukaryotic Translation Initiation Factors in Gene ExpressionR01CA200913 · NCI · HARVARD MEDICAL SCHOOL · PI WAGNER, GERHARD · 2016 to 2020
$2.3M
Deciphering GPCR signal transduction through NMR structure and dynamics studiesK99GM115814 · NIGMS · HARVARD MEDICAL SCHOOL · PI ZIAREK, JOSHUA JAMES · 2015 to 2016
$180k
Austrian Science Fund FWF J 3872NCI NIH HHS R01 CA200913NIBIB NIH HHS P41 EB002026NIGMS NIH HHS K99 GM115814NIGMS NIH HHS P01 GM047467
6 · The paper itself

Abstract

Studies over the past decade have highlighted the functional significance of intrinsically disordered proteins (IDPs). Due to conformational heterogeneity and inherent dynamics, structural studies of IDPs have relied mostly on NMR spectroscopy, despite IDPs having characteristics that make them challenging to study using traditional

Indexed as

Magnetic Resonance SpectroscopyNFATC Transcription FactorsNitrogen IsotopesProtein ConformationNFATC2 protein, humanNFATC Transcription FactorsNitrogen-15Nitrogen Isotopes15N detectionIDPNFATNMR resonance assignmentnuclear localization

Identifiers

PMID29432148
PMCPMC5828609
OpenAlexW2787291370

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.