Evidence map›Paper›PMID 29432091›Full record

ArticleEmerging infectious diseases2018

Influenza A(H7N9) Virus Antibody Responses in Survivors 1 Year after Infection, China, 2017.

Mai-Juan Ma, Cheng Liu, Meng-Na Wu, Teng Zhao, Guo-Lin Wang, Yang Yang, Hong-Jing Gu, Peng-Wei Cui, Yuan-Yuan Pang, Ya-Yun Tan and 6 more

Open access · diamondAbstract readHistorical Article
In one paragraph

Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Persistence of H7N9 virus antibody response 2 years after infection.Influenza and other respiratory viruses · 2020
    Article
  7. Characterization of antibody and memory T-cell response in H7N9 survivors: a cross-sectional analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2020
    Article
  8. Article
  9. Novel Avian Influenza A Virus Infections of Humans.Infectious disease clinics of North America · 2019
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Mai-Juan Ma
Cheng Liu
Meng-Na Wu
Teng Zhao
Guo-Lin Wang
Yang Yang
Hong-Jing Gu
Peng-Wei Cui
Yuan-Yuan Pang
Ya-Yun Tan
Hui Hang
Bao Lin
Jiang-Chun Qin
Li-Qun Fang
Wu-Chun Cao
Li-Ling Cheng
Institute of Microbiology · CNUniversity of Florida · USSuzhou Municipal Hospital · CN

Funding

Understanding Transmission with Integrated Genetic and Epidemiologic InferenceU54GM111274 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI VESPIGNANI, ALESSANDRO · 2014 to 2018
$12.5M
NIGMS NIH HHS U54 GM111274
6 · The paper itself

Abstract

Avian influenza A(H7N9) virus has caused 5 epidemic waves in China since its emergence in 2013. We investigated the dynamic changes of antibody response to this virus over 1 year postinfection in 25 patients in Suzhou City, Jiangsu Province, China, who had laboratory-confirmed infections during the fifth epidemic wave, October 1, 2016-February 14, 2017. Most survivors had relatively robust antibody responses that decreased but remained detectable at 1 year. Antibody response was variable; several survivors had low or undetectable antibody titers. Hemagglutination inhibition titer was >1:40 for <40% of the survivors. Measured in vitro in infected mice, hemagglutination inhibition titer predicted serum protective ability. Our findings provide a helpful serologic guideline for identifying subclinical infections and for developing effective vaccines and therapeutics to counter H7N9 virus infections.

Indexed as

AgedAnimalsAntibodies, ViralFemaleHistory, 21st CenturyHospitalizationHumansInfluenza A Virus, H7N9 SubtypeInfluenza, HumanMaleMiceMiddle AgedSerologic TestsSurvivorsAntibodies, Viralantibody responseChinacohortH7N9 virusesinfluenzainfluenza A(H7N9)persistenceserologicalsurvivorsviruses

Identifiers

PMID29432091
PMCPMC5875250
OpenAlexW2793918183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.