Evidence map›Paper›PMID 29431835›Full record

ReviewFood & function2018

Processing of oat: the impact on oat's cholesterol lowering effect.

Myriam M-L Grundy, Anthony Fardet, Susan M Tosh, Gillian T Rich, Peter J Wilde

Open access · hybridAbstract readReview
In one paragraph

Review in Food & function, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
8.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Edible Potential ofFood science & nutrition · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Validation of Appropriate Reference Genes for qRT-PCR Normalization in Oat (International journal of molecular sciences · 2022
    Article
  17. A Review of Health-Beneficial Properties of Oats.Foods (Basel, Switzerland) · 2021
    Review
  18. Multiple Antioxidative and Bioactive Molecules of Oats (Antioxidants (Basel, Switzerland) · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Myriam M-L GrundyFood and Health Programme, Quadram Institute Bioscience, Norwich Research Park, NR4 7UA, UK. myriam.grundy@quadram.ac.uk wildongillian@gmail.com peter.wilde@quadram.ac.uk.ORCID http://orcid.org/0000-0001-7162-656X
Anthony FardetINRA, JRU 1019, UNH, CRNH Auvergne, F-63000 Clermont-Ferrand & Université de Clermont, Université d'Auvergne, Unité de Nutrition Humaine, BP 10448, F-63000 Clermont-Ferrand, France. anthony.fardet@inra.fr.ORCID http://orcid.org/0000-0003-4972-9217
Susan M ToshUniversity of Ottawa, Université, Salle 118, Ottawa, ON K1N 6N5 Canada. Susan.Tosh@uottawa.ca.ORCID http://orcid.org/0000-0002-3733-3808
Gillian T RichFood and Health Programme, Quadram Institute Bioscience, Norwich Research Park, NR4 7UA, UK. myriam.grundy@quadram.ac.uk wildongillian@gmail.com peter.wilde@quadram.ac.uk.
Peter J WildeFood and Health Programme, Quadram Institute Bioscience, Norwich Research Park, NR4 7UA, UK. myriam.grundy@quadram.ac.uk wildongillian@gmail.com peter.wilde@quadram.ac.uk.ORCID http://orcid.org/0000-0003-2001-4066
World Food Programme · ITUniversité Clermont Auvergne · FRUniversity of Ottawa · CA

Funding

Biotechnology and Biological Sciences Research Council BB/H004866/1
6 · The paper itself

Abstract

Epidemiological and interventional studies have clearly demonstrated the beneficial impact of consuming oat and oat-based products on serum cholesterol and other markers of cardiovascular disease. The cholesterol-lowering effect of oat is thought to be associated with the β-glucan it contains. However, not all food products containing β-glucan seem to lead to the same health outcome. Overall, highly processed β-glucan sources (where the oat tissue is highly disrupted) appear to be less effective at reducing serum cholesterol, but the reasons are not well understood. Therefore, the mechanisms involved still need further clarification. The purpose of this paper is to review current evidence of the cholesterol-lowering effect of oat in the context of the structure and complexity of the oat matrix. The possibility of a synergistic action and interaction between the oat constituents promoting hypocholesterolaemia is also discussed. A review of the literature suggested that for a similar dose of β-glucan, (1) liquid oat-based foods seem to give more consistent, but moderate reductions in cholesterol than semi-solid or solid foods where the results are more variable; (2) the quantity of β-glucan and the molecular weight at expected consumption levels (∼3 g day

Indexed as

AnimalsAnticholesteremic AgentsAvenabeta-GlucansCholesterolHumansHypercholesterolemiaAnticholesteremic Agentsbeta-GlucansCholesterol

Identifiers

PMID29431835
PMCPMC5885279
OpenAlexW2787033500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.