Evidence map›Paper›PMID 29431433›Full record

ArticleJournal of the American Chemical Society2018

Supramolecular Assemblies for Transporting Proteins Across an Immiscible Solvent Interface.

Jingjing Gao, Bo Zhao, Meizhe Wang, Mahalia A C Serrano, Jiaming Zhuang, Moumita Ray, Vincent M Rotello, Richard W Vachet, S Thayumanavan

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Tunable Polymeric Scaffolds for Enzyme Immobilization.Frontiers in bioengineering and biotechnology · 2020
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jingjing GaoDepartment of Chemistry, University of Massachusetts , Amherst, Massachusetts 01003, United States.
Bo ZhaoDepartment of Chemistry, University of Massachusetts , Amherst, Massachusetts 01003, United States.
Meizhe WangDepartment of Chemistry, University of Massachusetts , Amherst, Massachusetts 01003, United States.
Mahalia A C SerranoDepartment of Chemistry, University of Massachusetts , Amherst, Massachusetts 01003, United States.
Jiaming ZhuangDepartment of Chemistry, University of Massachusetts , Amherst, Massachusetts 01003, United States.
Moumita RayDepartment of Chemistry, University of Massachusetts , Amherst, Massachusetts 01003, United States.
Vincent M RotelloDepartment of Chemistry, University of Massachusetts , Amherst, Massachusetts 01003, United States.ORCID 0000-0002-5184-5439
Richard W VachetDepartment of Chemistry, University of Massachusetts , Amherst, Massachusetts 01003, United States.ORCID 0000-0003-4514-0210
S ThayumanavanDepartment of Chemistry, University of Massachusetts , Amherst, Massachusetts 01003, United States.ORCID 0000-0002-6475-6726

Funding

CHEMISTRY-BIOLOGY INTERFACE PREDOCTORAL TRAINING GRANTST32GM008515 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI THOMPSON, LYNMARIE K. · 1995 to 2020
$4.3M
Supramolecular Assemblies for Detecting Biomarkers in Complex MixturesR01CA169140 · NCI · UNIVERSITY OF MASSACHUSETTS AMHERST · PI THAYUMANAVAN, SANKARAN · 2013 to 2017
$1.7M
NCI NIH HHS R01 CA169140NIGMS NIH HHS T32 GM008515
6 · The paper itself

Abstract

Polymeric supramolecular assemblies that can effectively transport proteins across an incompatible solvent interface are described. We show that electrostatics and ligand-protein interactions can be used to selectively transport proteins from an aqueous phase to organic phase. These transported proteins have been shown to maintain their tertiary structure and function. This approach opens up new possibilities for application of supramolecular assemblies in sensing, diagnostics and catalysis.

Indexed as

Carrier ProteinsLigandsMacromolecular SubstancesMolecular StructureParticle SizeQuinolinesSolventsStatic Electricitybicinchoninic acidCarrier ProteinsLigandsMacromolecular SubstancesQuinolinesSolvents

Identifiers

PMID29431433
PMCPMC6174083

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.