Evidence map›Paper›PMID 29431053›Full record

ArticleTissue engineering. Part A2018

Nanoparticle-Mediated Cell Capture Enables Rapid Endothelialization of a Novel Bare Metal Stent.

Brandon J Tefft, Susheil Uthamaraj, Adriana Harbuzariu, J Jonathan Harburn, Tyra A Witt, Brant Newman, Peter J Psaltis, Ota Hlinomaz, David R Holmes, Rajiv Gulati and 3 more

Abstract read
In one paragraph

Article in Tissue engineering. Part A, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Magnetic Cell Targeting for Cardiovascular Tissue Engineering.Tissue engineering. Part B, Reviews · 2025
    Review
  3. Article
  4. Integral Algorithms to Evaluate TiOInternational journal of molecular sciences · 2022
    Article
  5. Article
  6. Article
  7. Histochemistry for nanomedicine: Novelty in tradition.European journal of histochemistry : EJH · 2021
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Brandon J Tefft1 Department of Cardiovascular Medicine, Mayo Clinic , Rochester, Minnesota.
Susheil Uthamaraj2 Division of Engineering, Mayo Clinic , Rochester, Minnesota.
Adriana Harbuzariu1 Department of Cardiovascular Medicine, Mayo Clinic , Rochester, Minnesota.
J Jonathan Harburn3 School of Pharmacy & Institute of Cellular Medicine, Newcastle University , Newcastle-upon-Tyne, United Kingdom .
Tyra A Witt1 Department of Cardiovascular Medicine, Mayo Clinic , Rochester, Minnesota.
Brant Newman2 Division of Engineering, Mayo Clinic , Rochester, Minnesota.
Peter J Psaltis4 Vascular Research Centre, South Australian Health and Medical Research Institute , Adelaide, Australia .
Ota Hlinomaz6 Department of Cardioangiology, St. Anne's University Hospital , Brno, Czech Republic .
David R Holmes1 Department of Cardiovascular Medicine, Mayo Clinic , Rochester, Minnesota.
Rajiv Gulati1 Department of Cardiovascular Medicine, Mayo Clinic , Rochester, Minnesota.
Robert D Simari1 Department of Cardiovascular Medicine, Mayo Clinic , Rochester, Minnesota.
Dan Dragomir-Daescu7 Department of Physiology and Biomedical Engineering, Mayo Clinic , Rochester, Minnesota.
Gurpreet S Sandhu1 Department of Cardiovascular Medicine, Mayo Clinic , Rochester, Minnesota.

Funding

CARDIOVASOLOGYT32HL007111 · NHLBI · MAYO CLINIC ROCHESTER · PI Barry A. Borlaug · 1985 to 2026
$8.7M
Nanotechnology for magnetic endothelialization of implantable cardiovascular devicesK99HL129068 · NHLBI · MAYO CLINIC ROCHESTER · PI TEFFT, BRANDON J · 2016 to 2017
$267k
NHLBI NIH HHS K99 HL129068NHLBI NIH HHS T32 HL007111
6 · The paper itself

Abstract

Incomplete endothelialization of intracoronary stents has been associated with stent thrombosis and recurrent symptoms, whereas prolonged use of dual antiplatelet therapy increases bleeding-related adverse events. Facilitated endothelialization has the potential to improve clinical outcomes in patients who are unable to tolerate dual antiplatelet therapy. The objective of this study was to demonstrate the feasibility of magnetic cell capture to rapidly endothelialize intracoronary stents in a large animal model. A novel stent was developed from a magnetizable duplex stainless steel (2205 SS). Polylactic-co-glycolic acid and magnetite (Fe

Indexed as

StentsAnimalsEndothelial CellsFemaleMetalsNanoparticlesPhenotypeStainless SteelSwineMetalsStainless Steelcell-targetingendothelializationmagnetic stentnanotechnology

Identifiers

PMID29431053
PMCPMC6033300

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.