ArticleOrthopaedic surgery2018
Low Grip Strength is a Strong Risk Factor of Osteoporosis in Postmenopausal Women.
Article in Orthopaedic surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of osteoporosis and incidence of related fractures in developed economies in the Asia Pacific region: a systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023Pooled it
- Trial
- Comprehensive Interventions Including Vitamin D Effectively Reduce the Risk of Falls in Elderly Osteoporotic Patients.Orthopaedic surgery · 2021Trial
- Minimum pulse rate during sleep as a MMSE-associated factor: a multifaceted exploratory study in older adults without long-term care certification.BMC geriatrics · 2025Article
- The relationship between osteoporosis and sarcopenia parameters in postmenopausal women under 60 years of age: A cross-sectional study.Irish journal of medical science · 2025Article
- Association between sarcopenia, its components, and osteoporosis in the FRISBEE cohort.BMC musculoskeletal disorders · 2025Article
- Article
- Predictors of hip fracture in 15 European countries: a longitudinal study of 48,533 geriatric adults using SHARE dataset.Archives of osteoporosis · 2024Article
- Identifying characteristics and clinical conditions associated with hand grip strength in adults: the Project Baseline Health Study.Scientific reports · 2024Article
- Effects of Frailty Syndrome on Osteoporosis, Focusing on the Mediating Effect of Muscle Strength and Balance in Community-Dwelling Older Adults (≥60 years) in Iran: Results From the Amirkola Health and Aging Project Cohort Study.Geriatric orthopaedic surgery & rehabilitation · 2024Article
- The genetic causal effect of hand grip strength on osteoporosis and falling risk: a Mendelian randomization study.Frontiers in endocrinology · 2024Article
- Hand Grip Strength, Osteoporosis, and Quality of Life in Middle-Aged and Older Adults.Medicina (Kaunas, Lithuania) · 2023Article
- Article
- The Relationship Between Muscular Strength, Jump Power, and Bone Health in Collegiate Distance Runners.International journal of exercise science · 2023Article
- Comprehensive Geriatric Assessment in the Emergency Department for Identifying Elderly Individuals at Risk of Hip Fracture.Journal of acute medicine · 2022Article
- Is sarcopenia associated with osteoporosis? A cross-sectional study of 262 women with hip fracture.European journal of physical and rehabilitation medicine · 2022Article
- A bi-directional Mendelian randomization study of the sarcopenia-related traits and osteoporosis.Aging · 2022Article
- Association between fat mass by bioelectrical impedance analysis and bone mass by quantitative ultrasound in relation to grip strength and serum 25-hydroxyvitamin D in postmenopausal Japanese women: the Unzen study.Journal of physiological anthropology · 2022Article
- Unilateral hand force control impairments in older women.EXCLI journal · 2022Article
- Causal associations of hand grip strength with bone mineral density and fracture risk: A mendelian randomization study.Frontiers in endocrinology · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the effect of grip strength on bone mineral density (BMD) in postmenopausal women. Low BMD is related to risk of fracture and falling is the strongest factor for fragility fractures. Handgrip strength is a reliable indicator of muscle strength and muscle strength is associated with falling.
methodsFor the present study 120 women were divided into two groups: those ≤65 years and those >65 years. Serum 25 hydroxyvitamin D (25OHD), BMD, and handgrip strength were measured to observe the effect of age on 25OHD, grip strength, and BMD, as well as the effect of 25OHD on grip strength and BMD. The correlation between grip strength and BMD was investigated.
resultsIn the 120 patients, 25OHD was 24.31 ± 8.29 ng/mL. There were 37 cases with 25OHD <20 ng/mL and 83 cases with 25 OHD ≥20 ng/mL. The patients with 25OHD <20 ng/mL had significantly lower femoral neck BMD, most of them with a T score ≤-2.5 (P < 0.05). BMD measurement showed 66 patients with femoral neck T ≤-2.5, 30 cases with total hip T ≤-2.5 and 90 cases with lumbar BMD T ≤-2.5. The maximum grip strength in the group is 22.28 ± 6.17 kg. There were 38 cases with the maximum grip strength <20 kg and 82 cases with the maximum grip strength ≥20 kg. Patients >65 years had lower 25OHD, lower maximum grip strength, and lower BMD. The osteoporosis risk in postmenopausal women with a maximum grip strength <20 kg and who were >65 years was significantly elevated.
conclusionHandgrip strength and 25OHD decrease with aging in postmenopausal women. The patients with lower 25OHD level had significantly lower BMD of femoral neck. The patients with lower handgrip strength had significantly lower BMD of lumbar spine, femoral neck, and total hip. Grip strength measurement is the simplest muscle strength measurement method. Our study confirmed that low grip strength was correlated with low BMD and was a strong risk factor for osteoporosis in postmenopausal women.
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