ReviewNeuroscience bulletin2018
The Antidepressant Effect of Light Therapy from Retinal Projections.
Review in Neuroscience bulletin, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 44 citations in OpenAlex.
- The effect of bright light therapy on glycemic control and cortisol rhythmicity in depression: a randomized controlled trial.Frontiers in psychiatry · 2026Trial
- Harnessing the power of targeted metal nanocarriers mediated photodynamic and photothermal therapy.Nanomedicine (London, England) · 2026Review
- Connectome-based growth models reveal individual heterogeneity and neurophysiological subtypes of subthreshold depression.Molecular psychiatry · 2026Article
- Novel and emerging physical treatments for major depressive disorder.Fundamental research · 2025Review
- The role of artificial intelligence in the diagnosis of diabetic retinopathy through retinal lesion features: a narrative review.Quantitative imaging in medicine and surgery · 2025Review
- Evaluation of the impact of a 8 week exposure to a portable light therapy device, Luminette®, on retinal function assessed by ElectroRetinoGraphy.Current research in toxicology · 2025Article
- Outdoor daylight exposure and longer sleep promote wellbeing under COVID-19 mandated restrictions.Journal of sleep research · 2022Article
- Subclinical alterations of resting state functional brain network for adjunctive bright light therapy in nonseasonal major depressive disorder: A double blind randomized controlled trial.Frontiers in neurology · 2022Article
- Major Depressive Disorder: Advances in Neuroscience Research and Translational Applications.Neuroscience bulletin · 2021Review
- Computer Vision for Brain Disorders Based Primarily on Ocular Responses.Frontiers in neurology · 2021Article
- E3 ubiquitin ligase HRD1 modulates the circadian clock through regulation of BMAL1 stability.Experimental and therapeutic medicine · 2020Article
- NLRP3 Deficiency Attenuates Secondary Degeneration of Visual Cortical Neurons Following Optic Nerve Injury.Neuroscience bulletin · 2020Article
- Regulation of Circadian Genes by the MAPK Pathway: Implications for Rapid Antidepressant Action.Neuroscience bulletin · 2020Review
- Role of PPARs in Progression of Anxiety: Literature Analysis and Signaling Pathways Reconstruction.PPAR research · 2020Review
- Research progress on the neural mechanism of light therapy improving cognitive function in depression: from retinal projections to neuroplasticity.Frontiers in neurologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Observations from clinical trials have frequently demonstrated that light therapy can be an effective therapy for seasonal and non-seasonal major depression. Despite the fact that light therapy is known to have several advantages over antidepressant drugs like a low cost, minimal side-effects, and fast onset of therapeutic effect, the mechanism underlying light therapy remains unclear. So far, it is known that light therapy modulates mood states and cognitive functions, involving circadian and non-circadian pathways from retinas into brain. In this review, we discuss the therapeutic effect of light on major depression and its relationship to direct retinal projections in the brain. We finally emphasize the function of the retino-raphe projection in modulating serotonin activity, which probably underlies the antidepressant effect of light therapy for depression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.