ArticleAnnals of translational medicine2018
Interaction between peri-operative blood transfusion, tidal volume, airway pressure and postoperative ARDS: an individual patient data meta-analysis.
Article in Annals of translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Risk assessment and prevention of postoperative and postprocedural respiratory failure: recommendations from an international expert panel.British journal of anaesthesia · 2026Guideline
- Postoperative ARDS: distinct etiologies, distinct priorities.Intensive care medicine · 2026Article
- Dynamic and interpretable deep learning model for predicting respiratory failure following cardiac surgery.BMC anesthesiology · 2025Article
- Case report: Causes of acute respiratory distress syndrome complications after lung resection.SAGE open medical case reports · 2025Article
- Bronchial Blockers versus Double-Lumen Endotracheal Tubes: Impact on Postoperative Pneumonia in Lung Cancer Patients Undergoing Video-Assisted Thoracoscopic Surgery - A Propensity Score-Matched Study.Risk management and healthcare policy · 2025Article
- Comparison of early postoperative pulmonary complications between two-lung ventilation with artificial pneumothorax and one-lung ventilation with bronchial blockade in patients undergoing minimally invasive esophagectomy: a retrospective propensity score-matched cohort study.Journal of thoracic disease · 2024Article
- Perioperative Risk Factors for Postoperative Pulmonary Complications After Minimally Invasive Esophagectomy.International journal of general medicine · 2024Article
- Comparative risk of pulmonary adverse events with transfusion of pathogen reduced and conventional platelet components.Transfusion · 2022Article
- The association between double-lumen tube versus bronchial blocker and postoperative pulmonary complications in patients after lung cancer surgery.Frontiers in oncology · 2022Article
- Risk factors for unplanned reintubation caused by acute airway compromise after general anesthesia: a case-control study.BMC anesthesiology · 2021Article
- Transfusion in the mechanically ventilated patient.Intensive care medicine · 2020Review
- Red-blood-cell manufacturing methods and storage solutions differentially induce pulmonary cell activation.Vox sanguinis · 2020Article
- Perioperative anaesthetic management of patients with or at risk of acute distress respiratory syndrome undergoing emergency surgery.BMC anesthesiology · 2019Review
Corrections and comments
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Authors and funding
34 authors at 13 institutions in 9 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTransfusion of blood products and mechanical ventilation with injurious settings are considered risk factors for postoperative lung injury in surgical Patients.
methodsA systematic review and individual patient data meta-analysis was done to determine the independent effects of peri-operative transfusion of blood products, intra-operative tidal volume and airway pressure in adult patients undergoing mechanical ventilation for general surgery, as well as their interactions on the occurrence of postoperative acute respiratory distress syndrome (ARDS). Observational studies and randomized trials were identified by a systematic search of MEDLINE, CINAHL, Web of Science, and CENTRAL and screened for inclusion into a meta-analysis. Individual patient data were obtained from the corresponding authors. Patients were stratified according to whether they received transfusion in the peri-operative period [red blood cell concentrates (RBC) and/or fresh frozen plasma (FFP)], tidal volume size [≤7 mL/kg predicted body weight (PBW), 7-10 and >10 mL/kg PBW] and airway pressure level used during surgery (≤15, 15-20 and >20 cmH
resultsSeventeen investigations were included (3,659 patients). Postoperative ARDS occurred in 40 (7.2%) patients who received at least one blood product compared to 40 patients (2.5%) who did not [adjusted hazard ratio (HR), 2.32; 95% confidence interval (CI), 1.25-4.33; P=0.008]. Incidence of postoperative ARDS was highest in patients ventilated with tidal volumes of >10 mL/kg PBW and having airway pressures of >20 cmH
conclusionsPeri-operative transfusion of blood products is associated with an increased risk of postoperative ARDS, which seems more dependent on airway pressure than tidal volume size.
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