Evidence map›Paper›PMID 29430300›Full record

ArticleJournal of materials chemistry. B2017

Responsive Hybrid (Poly)peptide-Polymer Conjugates.

Bradford A Paik, Shivshankar R Mane, Xinqiao Jia, Kristi L Kiick

Abstract read
In one paragraph

Article in Journal of materials chemistry. B, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
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  4. Review
  5. Article
  6. Article
  7. Formulation of Poloxamers for Drug Delivery.Journal of functional biomaterials · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bradford A PaikDepartment of Materials Science and Engineering, University of Delaware, 201 DuPont Hall, Newark, DE 19716-3106.
Shivshankar R ManeThe Institude For Chemical Technology and Polymer Chemistry, Karlsruhe Institute of Technology, Engesserstr. 18, 76128 Karlsruhe, Germany.
Xinqiao JiaDepartment of Materials Science and Engineering, University of Delaware, 201 DuPont Hall, Newark, DE 19716-3106.
Kristi L KiickDepartment of Materials Science and Engineering, University of Delaware, 201 DuPont Hall, Newark, DE 19716-3106.

Funding

Biotechnology Research Partnerships Renewal: Aggregation of Therapeutic ProteinsR01EB006006 · NIBIB · UNIVERSITY OF COLORADO · PI RANDOLPH, THEODORE W · 2006 to 2017
$7.2M
Pilot Research Subproject ProgramP30GM110758 · NIGMS · UNIVERSITY OF DELAWARE · PI BEEBE, THOMAS PAUL · 2014 to 2018
$5.8M
COBRE on Membrane Protein Production and CharacterizationP30GM103519 · NIGMS · UNIVERSITY OF DELAWARE · PI LENHOFF, ABRAHAM M · 2012 to 2014
$3.3M
NIBIB NIH HHS R01 EB006006NIGMS NIH HHS P30 GM103519NIGMS NIH HHS P30 GM110758
6 · The paper itself

Abstract

(Poly)peptide-polymer conjugates continue to garner significant interest in the production of functional materials given their composition of natural and synthetic building blocks that confer select and synergistic properties. Owing to opportunities to design predefined architectures and structures with different morphologies, these hybrid conjugates enable new approaches for producing micro- or nanomaterials. Their modular design enables the incorporation of multiple responsive properties into a single conjugate. This review presents recent advances in (poly)peptide-polymer conjugates for drug-delivery applications, with a specific focus on the utility of the (poly)peptide component in the assembly of particles and nanogels, as well as the role of the peptide in triggered drug release.

Identifiers

PMID29430300
PMCPMC5802422

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.