Evidence map›Paper›PMID 29430167›Full record

ArticleMolecular vision2018

The genetic dissection of

Ye Lu, Diana Zhou, Rebecca King, Shuang Zhu, Claire L Simpson, Byron C Jones, Wenbo Zhang, Eldon E Geisert, Lu Lu

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Molecular vision, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Dual-AAV vector-mediated expression ofMolecular therapy. Methods & clinical development · 2023
    Article
  2. Article
  3. Review
  4. Article
  5. Exploring the Role of Chemokine Receptor 6 (Frontiers in neuroscience · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ye LuDepartment of Ophthalmology, The First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, China.
Diana ZhouDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN.
Rebecca KingDepartment of Ophthalmology and Emory Eye Center, Emory University, Atlanta, GA.
Shuang ZhuDepartment of Ophthalmology & Visual Sciences, University of Texas Medical Branch, Galveston, TX.
Claire L SimpsonDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN.
Byron C JonesDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN.
Wenbo ZhangDepartment of Ophthalmology & Visual Sciences, University of Texas Medical Branch, Galveston, TX.
Eldon E GeisertDepartment of Ophthalmology and Emory Eye Center, Emory University, Atlanta, GA.
Lu LuDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN.
University of Tennessee Health Science Center · USEmory Eye Center · USThe University of Texas Medical Branch at Galveston · US

Funding

P30-Core Grant for Vision Research Core CP30EY006360 · NEI · EMORY UNIVERSITY · PI NICKERSON, JOHN M · 1986 to 2025
$15.3M
Mechanisms of Retinal Neuronal InjuryR01EY022694 · NEI · UNIVERSITY OF TEXAS MED BR GALVESTON · PI ZHANG, WENBO · 2012 to 2021
$3.8M
Genetic Modulators of GlaucomaR01EY021200 · NEI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI JABLONSKI, MONICA M · 2011 to 2022
$3.2M
Modulators of Retinal InjuryR01EY017841 · NEI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI GEISERT, ELDON E · 2007 to 2016
$3.0M
Pathogenic Role of EPAC1 Signaling in Retinopathy of PrematurityR01EY026629 · NEI · UNIVERSITY OF TEXAS MED BR GALVESTON · PI ZHANG, WENBO · 2017 to 2021
$2.6M
NEI NIH HHS P30 EY006360NEI NIH HHS R01 EY017841NEI NIH HHS R01 EY021200NEI NIH HHS R01 EY022694NEI NIH HHS R01 EY026629
6 · The paper itself

Abstract

Purpose: Usher syndrome (US) is characterized by a loss of vision due to retinitis pigmentosa (RP) and deafness. US has three clinical subtypes, but even within each subtype, the severity varies. Myosin VIIA, coded by Methods: In this study, we used the retinal tissue of BXD recombinant inbred (RI) mice to examine the expression of Results: We found Conclusions: Although

Indexed as

Gene Regulatory NetworksQuantitative Trait LociAnimalsCrosses, GeneticDisease Models, AnimalFemaleGene Expression ProfilingGene Expression RegulationGene OntologyHumansMaleMiceMice, Inbred C57BLMice, Inbred DBAMolecular Sequence AnnotationMyosinsMYO7A protein, humanMyo7a protein, mouseMyosinsMyosin VIIaTranscription Factors

Identifiers

PMID29430167
PMCPMC5802760
OpenAlexW2801797636

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.