Evidence map›Paper›PMID 29429938›Full record

ArticleNeuron2018

Signaling Mode of the Broad-Spectrum Conserved CO

Dyan MacWilliam, Joel Kowalewski, Arun Kumar, Crystal Pontrello, Anandasankar Ray

Abstract read
In one paragraph

Article in Neuron, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Noses on the wing: the olfactory capacity of hawkmoth wings.The Journal of experimental biology · 2026
    Article
  2. Article
  3. Hawkmoths can smell with grooming organs on their legs.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Plant-associated COeLife · 2021
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Dyan MacWilliamDepartment of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, CA 92521, USA.
Joel KowalewskiInterdepartmental Neuroscience Program, University of California, Riverside, Riverside, CA 92521, USA.
Arun KumarDepartment of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, CA 92521, USA.
Crystal PontrelloDepartment of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, CA 92521, USA.
Anandasankar RayDepartment of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, CA 92521, USA; Interdepartmental Neuroscience Program, University of California, Riverside, Riverside, CA 92521, USA. Electronic address: anand.ray@ucr.edu.

Funding

Disruption of Host-Seeking Behavior in Aedes and Culex Mosquitoes using OdorantsR01AI087785 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI RAY, ANANDASANKAR · 2010 to 2014
$1.8M
Functional analysis of insect taste receptorsR01DC013587 · NIDCD · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI DAHANUKAR, ANUPAMA ARUN · 2014 to 2018
$1.8M
Receptors and Circuits for DEET Detection and Improving RepellentsR01DC014092 · NIDCD · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI RAY, ANANDASANKAR · 2015 to 2019
$1.6M
NIAID NIH HHS R01 AI087785NIDCD NIH HHS R01 DC013587NIDCD NIH HHS R01 DC014092
6 · The paper itself

Abstract

Odor detection involves hundreds of olfactory receptors from diverse families, making modeling of hedonic valence of an odorant difficult, even in Drosophila melanogaster where most receptors have been deorphanised. We demonstrate that a broadly tuned heteromeric receptor that detects CO

Indexed as

OdorantsAedesAnimalsAnimals, Genetically ModifiedCarbon DioxideDrosophila melanogasterFemaleHumansMaleMaze LearningReceptors, Cell SurfaceReceptors, OdorantSignal TransductionSmellCarbon Dioxidecarbon dioxide receptorReceptors, Cell SurfaceReceptors, OdorantDrosophilaGr21aGr63agustatory receptorolfactionolfactory receptorOrcovalence

Identifiers

PMID29429938
PMCPMC5871350

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.