Evidence map›Paper›PMID 29429150›Full record

ArticleMolecules and cells2018

MiR-199a/b-5p Inhibits Lymphangiogenesis by Targeting Discoidin Domain Receptor 1 in Corneal Injury.

Sooeun Oh, Minkoo Seo, Jun-Sub Choi, Choun-Ki Joo, Suk Kyeong Lee

Open access · greenAbstract read
In one paragraph

Article in Molecules and cells, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sooeun OhDepartment of Medical Lifescience, The Catholic University of Korea, Seoul 06591, Korea.
Minkoo SeoDepartment of Medical Lifescience, The Catholic University of Korea, Seoul 06591, Korea.
Jun-Sub ChoiCatholic Institute for Visual Science, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Choun-Ki JooCatholic Institute for Visual Science, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Suk Kyeong LeeDepartment of Medical Lifescience, The Catholic University of Korea, Seoul 06591, Korea.
Catholic University of Korea · KRThe Catholic University of Korea Seoul St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Discoidin domain receptor 1 (DDR1) is involved in tumorigenesis and angiogenesis. However, its role in lymphangiogenesis has been unknown. Here, we tested whether downregulation of DDR1 expression by miR-199a/b can suppress lymphangiogenesis. We also aimed to identify miRNA target site(s) in the 3' untranslated region (UTR) of

Indexed as

Gene Expression Regulation3' Untranslated RegionsAnimalsCells, CulturedCorneal InjuriesDiscoidin Domain Receptor 1Disease Models, AnimalEndothelial CellsHEK293 CellsHumansLymphangiogenesisMicroRNAsNeovascularization, PathologicNeovascularization, PhysiologicRats3' Untranslated RegionsDiscoidin Domain Receptor 1MicroRNAsmirn199 microRNA, humancorneal injuriesDDR1endothelial cellhsa-miR-199lymphangiogenesis

Identifiers

PMID29429150
PMCPMC5824028
OpenAlexW2918613202

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.