Evidence map›Paper›PMID 29429043›Full record

ArticleDermatology and therapy2018

Treatment Patterns, Healthcare Resource Utilization, and Spending Among Medicaid-Enrolled Children with Chronic Idiopathic/Spontaneous Urticaria in the United States.

Paul V Williams, Abhishek Kavati, Dominic Pilon, Yongling Xiao, Maryia Zhdanava, Maria-Magdalena Balp, Patrick Lefebvre, Benjamin Ortiz, Vivian Hernandez-Trujillo

Open access · goldAbstract read
In one paragraph

Article in Dermatology and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Paul V WilliamsNorthwest Asthma and Allergy Center, Everett, WA, USA.
Abhishek KavatiNovartis Pharmaceuticals Corporation, East Hanover, NY, USA.
Dominic PilonAnalysis Group, Inc, Montréal, QC, Canada. dominic.pilon@analysisgroup.com.ORCID http://orcid.org/0000-0002-0778-9564
Yongling XiaoAnalysis Group, Inc, Montréal, QC, Canada.
Maryia ZhdanavaAnalysis Group, Inc, Montréal, QC, Canada.
Maria-Magdalena BalpNovartis Pharma AG, Basel, Switzerland.
Patrick LefebvreAnalysis Group, Inc, Montréal, QC, Canada.
Benjamin OrtizNovartis Pharmaceuticals Corporation, East Hanover, NY, USA.
Vivian Hernandez-TrujilloHerbert Wertheim School of Medicine, Florida International University, Miami, FL, USA.
Novartis (United States) · USFlorida International University · USGroup for Research in Decision Analysis · CANovartis (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFew studies have described chronic idiopathic/spontaneous urticaria (CIU/CSU) healthcare burden in adults, while this information remains largely unknown in children. We aimed to describe treatment patterns, healthcare resource utilization (HRU), and costs in CIU/CSU pediatric patients, as well as to compare HRU and costs in CIU/CSU and CIU/CSU-free pediatric patients.

methodsMedicaid claims from four states (09/01/2013-03/31/2016) were used to identify patients less than 12 years old. The CIU/CSU cohort included patients with either at least two claims for idiopathic, other, or unspecified urticaria at least 6 weeks apart, or at least one claim for urticaria and at least one claim for angioedema at least 6 weeks apart (index date defined as the first claim). The control cohort included patients without urticaria/angioedema claims (index date randomly assigned). Patients without at least 6 months of continuous Medicaid eligibility pre- and post-index were excluded. HRU and costs were compared between propensity score-matched cohorts during the post-index follow-up.

resultsA total of 548 CIU/CSU patients (mean [SD] age 4.5 [3.3] years; 51.3% male) were matched 1:1 with controls. In the CIU/CSU cohort, 51.8% used non-sedating prescription H

conclusionsCIU/CSU pediatric patients had low use of non-sedating H

fundingNovartis Pharmaceuticals Corporation.

Indexed as

ChildrenChronic idiopathic urticariaChronic spontaneous urticariaHealthcare burdenHealthcare resource utilizationMedicaidPediatricTreatment patterns

Identifiers

PMID29429043
PMCPMC5825330
OpenAlexW2791688326

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.