Evidence map›Paper›PMID 29429006›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2018

Exercise capacity and cancer-specific quality of life following curative intent treatment of stage I-IIIA lung cancer.

Duc Ha, Andrew L Ries, Peter J Mazzone, Scott M Lippman, Mark M Fuster

Registry-linked trialAbstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05179408 (Telerehabilitation for Veteran Lung Cancer Survivors Following Curative Intent Therapy), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05179408 narecruitingnot on this mapstarted 2026, after this paper: background citation

Telerehabilitation for Veteran Lung Cancer Survivors Following Curative Intent Therapy

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2026 to 2027Enrolled40ConditionsLung Cancer, Cancer SurvivorsArmsTargeted-telerehabilitation, Waitlist
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Telemedicine-based inspiratory muscle training and walking promotion with lung cancer survivors following curative intent therapy: a parallel-group pilot randomized trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Trial
  3. Trial
  4. Survivorship Challenges and Supportive Care in Lung Cancer.Seminars in respiratory and critical care medicine · 2025
    Review
  5. Article
  6. Barriers to and enablers of physical activity participation in lung cancer survivors.PM & R : the journal of injury, function, and rehabilitation · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Effects of curative-intent lung cancer therapy on functional exercise capacity and patient-reported outcomes.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Observational
  12. Impact of pre-radiation therapy quality of life in lung cancer survival: a prospective, intention-to-treat, multicenter study.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2020
    Article
  13. Characterization of Dyspnea in Veteran Lung Cancer Survivors Following Curative-Intent Therapy.Journal of cardiopulmonary rehabilitation and prevention · 2020
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Duc HaDivision of Pulmonary, Critical Care, and Sleep Medicine, University of California San Diego, 9300 Campus Point Drive, MC 7381, La Jolla, CA, 92037, USA. d5ha@ucsd.edu.ORCID http://orcid.org/0000-0002-3003-9438
Andrew L RiesDivision of Pulmonary, Critical Care, and Sleep Medicine, University of California San Diego, 9300 Campus Point Drive, MC 7381, La Jolla, CA, 92037, USA.
Peter J MazzoneCleveland Clinic, Respiratory Institute, 9500 Euclid Avenue, MC A90, Cleveland, OH, 44195, USA.
Scott M LippmanMoores Cancer Center, University of California San Diego, 9500 Gilman Drive, MC 0658, La Jolla, CA, 92093, USA.
Mark M FusterDivision of Pulmonary, Critical Care, and Sleep Medicine, University of California San Diego, 9300 Campus Point Drive, MC 7381, La Jolla, CA, 92037, USA.

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DIANE M SIMEONE · 1985 to 2026
$124.9M
UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
Training in the Next Generation in Respiratory ScienceT32HL134632 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL, POWELL, FRANK L. · 2017 to 2021
$2.1M
Lymphatic Microenvironment: Altering Cell Traffic by Targeting GlycansR01HL107652 · NHLBI · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI FUSTER, MARK M · 2012 to 2015
$1.2M
Assessment of Upper Airway Mechanics Using Newer Electromyographic TechniquesK24HL132105 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2016 to 2020
$611k
American Cancer Society PF-17-020-01-CPPBAmerican Lung Association LCD-400697EPA EP-D-17-020NCATS NIH HHS UL1 TR001442NCI NIH HHS 3P30CA023100-31NCI NIH HHS L30 CA208950NCI NIH HHS P30 CA023100NHLBI NIH HHS 1T32HL134632-01NHLBI NIH HHS K24 HL132105NHLBI NIH HHS R01 HL107652NHLBI NIH HHS R01-HL107652NHLBI NIH HHS T32 HL134632
6 · The paper itself

Abstract

purposeLung cancer survivors are at risk for health impairments resulting from the effects and/or treatment of lung cancer and comorbidities. Practical exercise capacity (EC) assessments can help identify impairments that would otherwise remain undetected. In this study, we characterized and analyzed the association between functional EC and cancer-specific quality of life (QoL) in lung cancer survivors who previously completed curative intent treatment.

methodsIn a cross-sectional study of 62 lung cancer survivors who completed treatment ≥ 1 month previously, we assessed functional EC with the 6-min walk distance (6MWD) and cancer-specific QoL with the European Organization for Research and Treatment of Cancer QoL Questionnaire Core 30 (EORTC-QLQ-C30). Cancer-specific QoL was defined using a validated composite EORTC-QLQ-C30 summary score. Univariable (UVA) and multivariable linear regression analyses (MVA) were performed to assess the relationship between functional EC and cancer-specific QoL.

resultsLung cancer survivors had reduced functional EC (mean 6MWD = 335 m, 65% predicted) and QoL (mean EORTC-QLQ-C30 summary score = 77, scale range 0-100). In UVA, 6MWD was significantly associated with cancer-specific QoL (R

conclusionsFunctional EC was independently associated with cancer-specific QoL in lung cancer patients postcurative intent treatment. Exercise-based interventions aimed at improving EC may improve cancer-specific QoL in these patients.

Indexed as

AgedCross-Sectional StudiesExerciseFemaleHumansLung NeoplasmsMaleNeoplasm StagingPatient Reported Outcome MeasuresQuality of LifeSurveys and QuestionnairesSurvivorshipLung cancerPatient-reported outcomeQuality of lifeSix-minute walk testSurvivorship

Identifiers

PMID29429006
PMCPMC6110278

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.