ArticleChild abuse & neglect2018
Childhood adversity increases the risk of onward transmission from perinatal HIV-infected adolescents and youth in South Africa.
Article in Child abuse & neglect, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Adverse Childhood Experiences in Non-Westernized Nations: Implications for Immigrant and Refugee Health.Journal of immigrant and minority health · 2020Pooled it
- The relationship between adverse childhood experiences and common mental disorders among pregnant women living with HIV in Malawi.Journal of affective disorders · 2022Trial
- An exploratory test of the pathways between adverse childhood experiences and later perpetration of intimate partner violence in South African male youth using theoretical frameworks.Child abuse & neglect · 2026Article
- Prevalence and incidence of physical and sexual intimate partner violence perpetration among adolescent boys living with and without HIV.Southern African journal of HIV medicine · 2026Article
- Association of childhood adversity and depression with cardiovascular health in youth with perinatal HIV 1 in Uganda.Discover public health · 2026Article
- The Impact of Childhood Household Violence on HIV-Related Outcomes in People With HIV in the United States: The Role of Psychological Distress and Social Stressors.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- Drivers of onward HIV transmission risk among adolescent boys growing up with HIV: a longitudinal cohort study.BMJ public health · 2025Article
- Mixed-method longitudinal investigation of sexual and gender-based violence following COVID-19 in South Africa.BMJ public health · 2025Article
- Associations between adverse childhood experiences, viral suppression, and quality of life among persons living with HIV in Washington state.AIDS care · 2024Article
- Pathways between adverse childhood experiences and viral suppression among male HIV-infected adolescents in South Africa.AIDS care · 2024Article
- Cohort profile: the Adverse Childhood Experiences cohort of the Malawi Longitudinal Study of Families and Health.BMJ open · 2024Article
- Patterns of adverse childhood experiences and their associations with mental distress, substance use and sexual risk behaviors in Sub-Saharan Africa.Child abuse & neglect · 2024Article
- Strong Father-Child Relationships and Other Positive Childhood Experiences, Adverse Childhood Experiences, and Sexual Risk Factors for HIV among Young Adults Aged 19-24 Years, Namibia, 2019: A Cross-Sectional Study.International journal of environmental research and public health · 2023Article
- "Is it worth living?" psychosocial challenges of childhood sexual abuse survivors aging with HIV.AIDS care · 2023Article
- Childhood Trauma and Mental Health in the Cape Town Adolescent Antiretroviral Cohort.Journal of child & adolescent trauma · 2022Article
- Predictors of secondary HIV transmission risk in a cohort of adolescents living with HIV in South Africa.AIDS (London, England) · 2022Article
- Adolescents and young adults with early acquired HIV infection in the united states: unique challenges in treatment and secondary prevention.Expert review of anti-infective therapy · 2021Review
- Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda.Journal of affective disorders reports · 2021Article
- "We need our own clinics": Adolescents' living with HIV recommendations for a responsive health system.PloS one · 2021Article
- High cellphone use associated with greater risk of depression among young women aged 15-24 years in Soweto and Durban, South Africa.Global health action · 2021Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
Repeated exposure to childhood adversity (abuse, neglect and other traumas experienced before age 18) can have lifelong impacts on health. For HIV-infected adolescents and youth, such impacts may include onward transmission of HIV. To evaluate this possibility, the current study measured the burden of childhood adversity and its influence on risky health behaviors among perinatally-infected adolescents and youth. We surveyed 250 perinatally-infected adolescents and youth (13-24 years) receiving care in Soweto, South Africa. Both male and female participants reported on childhood adversity (using the ACE-IQ), sexual behavior, and psychosocial state. Viral load was also abstracted from their charts. We used logistic regressions to test the association between cumulative adversity and behavioral outcomes. Half the sample reported eight or more adversities. Overall, 72% experienced emotional abuse, 59% experienced physical abuse, 34% experienced sexual abuse, 82% witnessed domestic violence, and 91% saw someone being attacked in their community. A clear gradient emerged between cumulative adversities and behavioral risk. Having experienced one additional childhood adversity raised the odds of risky sexual behavior by almost 30% (OR 1.27, 95% CI 1.09-1.48). Viral suppression was poor overall (31% had viral loads >400 copies/ml), but was not related to adversity. Adversity showed a robust relationship to depression and substance abuse. Childhood adversity is common, influences the current health of HIV-positive adolescents and youth, and puts their sexual partners at risk for HIV infection. Greater primary prevention of childhood adversity and increased access to support services (e.g., mental health) could reduce risk taking among HIV-positive adolescents and youth.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.