Evidence map›Paper›PMID 29428830›Full record

Trial reportContemporary clinical trials2018

The effect of a randomized controlled physical activity trial on health related quality of life in metabolically unhealthy African-American women: FIERCE STUDY.

Teletia R Taylor, Chiranjeev Dash, Vanessa Sheppard, Kepher Makambi, Xiaoyang Ma, Lucile L Adams-Campbell

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Contemporary clinical trials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Multidisciplinary Therapy to Target Obesity and Its Complications in Adult Population: A Narrative Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Teletia R TaylorHoward University Cancer Center, Howard University, Washington, DC, United States.
Chiranjeev DashGeorgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, United States.
Vanessa SheppardDepartment of Health Behavior and Policy, School of Medicine, Virginia Commonwealth University, Richmond, VA, United States.
Kepher MakambiDepartment of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University Medical Center, Washington, DC, United States.
Xiaoyang MaDepartment of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University Medical Center, Washington, DC, United States.
Lucile L Adams-CampbellGeorgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, United States. Electronic address: lla9@georgetown.edu.
Georgetown University Medical Center · USGeorgetown University · USHoward University · USVirginia Commonwealth University · US

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI Louis M Weiner · 1990 to 2026
$71.5M
Maternal Morbidity and Mortality: Risk Factors, Early Detection and Personalized InterventionUL1TR001409 · NCATS · GEORGETOWN UNIVERSITY · PI GONDRE-LEWIS, MARJORIE C, MELLMAN, THOMAS A · 2015 to 2024
$37.8M
Subproject 2: Verifying Information and Communication Technology and Outcomes P60MD006920 · NIMHD · GEORGETOWN UNIVERSITY · PI ADAMS-CAMPBELL, LUCILE LAUREN, KIDWELL, CHELSEA S · 2012 to 2016
$6.3M
Molecular Epidemiology of Oxidative Stress and Related Cancers in Black WomenK07CA197112 · NCI · GEORGETOWN UNIVERSITY · PI DASH, CHIRANJEEV · 2016 to 2020
$655k
NCATS NIH HHS UL1 TR001409NCI NIH HHS K07 CA197112NCI NIH HHS P30 CA051008NIMHD NIH HHS P60 MD006920
6 · The paper itself

Abstract

purposeAfrican-American women (AAW) are more likely to be metabolically unhealthy than White women (WW). Metabolic syndrome (MetS) is associated with increased breast cancer risk and mortality from breast cancer is greater in AAW compared to WW. Data show MetS affects health-related quality of life (HRQoL). Exercise studies report improvements in MetS, however, no study to date has examined HRQoL in metabolically unhealthy AAW enrolled in an exercise trial.

methodsThis report examined the effect of a 6-month, 3-arm (supervised exercise, home-based exercise, control) randomized exercise controlled trial on HRQoL among 213 obese, metabolically unhealthy, postmenopausal AAW at high risk for breast cancer.

resultsCertain baseline participant characteristics were related to baseline HRQoL dimensions. The "exercise group" (supervised group combined with the home-based group) showed significantly greater improvement in health change scores (M = 13.6, SD = 3.1) compared to the control group (M = 0.7, SD = 4.4) (p = 0.02) over the 6-month study period. There were no significant differences in HRQoL change scores between the 3 study groups, however, although non-significant, data indicated most HRQoL change scores were more favorable in the supervised group.

conclusionWhile significant improvement occurred in health change scores in the combined supervised and home-based group compared to the control group, we did not observe any significant differences on HRQoL change scores between all three study groups. However, while non-significant, there was a trend for more favorable HRQoL change scores in the supervised group versus the home-based and control groups. Additional research is needed to further explore this topic.

Indexed as

Metabolic SyndromeObesityQuality of LifeBlack or African AmericanBreast NeoplasmsDiet, ReducingExerciseExercise TherapyFemaleHealth Status DisparitiesHumansMiddle AgedOutcome Assessment, Health CarePostmenopauseWeight Reduction ProgramsBlacksExerciseMetabolic syndromeQuality of lifeWomen

Identifiers

PMID29428830
PMCPMC5871580
OpenAlexW3172506205

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.