Evidence map›Paper›PMID 29428524›Full record

ReviewEBioMedicine2018

The New Age of -omics in Urothelial Cancer - Re-wording Its Diagnosis and Treatment.

Theodora Katsila, Michalis Liontos, George P Patrinos, Aristotelis Bamias, Dimitrios Kardamakis

Open access · goldAbstract readReview
In one paragraph

Review in EBioMedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Role of main RNA modifications in cancer: NSignal transduction and targeted therapy · 2022
    Review
  3. Article
  4. Transcriptome-Wide Map of NFrontiers in oncology · 2021
    Article
  5. Article
  6. NEBioMedicine · 2019
    Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Theodora KatsilaDepartment of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece; Department of Radiation Oncology, University of Patras Medical School, Patras, Greece. Electronic address: thkatsila@upatras.gr.
Michalis LiontosDepartment of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece.
George P PatrinosDepartment of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece; Department of Pathology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Aristotelis BamiasDepartment of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece.
Dimitrios KardamakisDepartment of Radiation Oncology, University of Patras Medical School, Patras, Greece.
University of Patras · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unmet needs in urothelial cancer management represent an important challenge in our effort to improve long-term overall and disease-free survival rates with no significant compromise in quality of life. Radical cystectomy with pelvic lymph node dissection is the standard for the management of muscle-invasive, non-metastatic cancers. In spite of a 90% local disease control, up to 50% of patients ultimately die of distant metastasis. Bladder preservation using chemo-radiation is an acceptable alternative, but optimal patient selection remains elusive. Recent research is focused on the employment of tailored-made strategies in urothelial cancer exploiting the potential of theranostics in patient selection for specific therapies. Herein, we review the current knowledge on molecular theranostics in urothelial cancer and we suggest that this is the time to move toward imaging theranostics, if tailored-made disease management and patient stratification is envisaged.

Indexed as

GenomicsDiagnostic ImagingHumansPrecision MedicineTheranostic NanomedicineUrinary Bladder NeoplasmsUrotheliumImaging theranosticsMolecular theranosticsOmicsPrecision medicineUrothelial cancer

Identifiers

PMID29428524
PMCPMC5835572
OpenAlexW2793174734

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.