Evidence map›Paper›PMID 29427917›Full record

ArticleDrug and alcohol dependence2018

HIV treatment optimism and crystal methamphetamine use and initiation among HIV-negative men who have sex with men in Vancouver, Canada: A longitudinal analysis.

Sean P Colyer, Nathan J Lachowsky, Zishan Cui, Julia Zhu, Heather L Armstrong, Matthew Taylor, Joshua Edward, Gbolahan Olarewaju, Robert S Hogg, Eric A Roth and 1 more

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sean P ColyerBritish Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada; Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Canada. Electronic address: sean.colyer@mail.mcgill.ca.
Nathan J LachowskyBritish Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada; School of Public Health and Social Policy, University of Victoria, Victoria, Canada.
Zishan CuiBritish Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada.
Julia ZhuBritish Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada.
Heather L ArmstrongBritish Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada; Department of Medicine, University of British Columbia, Vancouver, Canada.
Matthew TaylorHealth Initiative for Men, Vancouver, Canada.
Joshua EdwardHealth Initiative for Men, Vancouver, Canada.
Gbolahan OlarewajuBritish Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada.
Robert S HoggBritish Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada; Faculty of Health Sciences, Simon Fraser University, Burnaby, Canada.
Eric A RothDepartment of Anthropology at the University of Victoria.
David M MooreBritish Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada; Department of Medicine, University of British Columbia, Vancouver, Canada.

Funding

Seek and Treat for Optimal Prevention of HIV & AIDS (STOP HIV/AIDS) in BCR01DA036307 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI MONTANER, JULIO SERGIO GONZALEZ · 2013 to 2017
$3.0M
HAART optimism, drug use and risky sexual behavior among MSM in British Columbia.R01DA031055 · NIDA · SIMON FRASER UNIVERSITY · PI HOGG, ROBERT S · 2011 to 2015
$2.0M
CIHR 14334CIHR MFE-152443CIHR MOP-107544CIHR PJT-15313NIDA NIH HHS R01 DA031055NIDA NIH HHS R01 DA036307
6 · The paper itself

Abstract

backgroundTreatment as Prevention (TasP) leading to increased HIV treatment optimism among men who have sex with men (MSM) has been previously associated with behavioural risk compensation, though not yet via crystal methamphetamine (CM) use. Among HIV-negative MSM in a TasP environment, this study aimed to investigate the prevalence of recent CM use over time, examine the association between HIV treatment optimism and CM use and initiation, and identify correlates of recent CM use and predictors of CM initiation.

methodsUsing data from a prospective behavioural cohort study of sexually active MSM in the Vancouver area, we used multi-level generalized mixed effect models to evaluate temporal trends in CM use, univariable and multivariable logistic regression to identify covariates of recent CM use, and univariable and multivariable survival analysis to identify predictors of CM initiation.

resultsOf 497 HIV-negative cohort participants, 10.3% reported any recent CM use at enrollment. From 2012-2016, there were no statistically significant temporal trends in overall CM use or with routes of administration. In multivariable logistic regression analyses, HIV treatment optimism was not associated with recent CM use (not retained in final model) or CM initiation (aHR = 1.06, 95% CI:0.98-1.15). Significant correlates of CM use include recent gamma-hydroxybutyrate (GHB) and ecstasy use, and having received/given drugs for sex.

conclusionsAmong HIV-negative MSM in Vancouver, HIV treatment optimism does not appear to be independently associated with CM use or initiation of use, though use of CM was both prevalent and stable over time.

Indexed as

MethamphetamineRisk-TakingAdultAmphetamine-Related DisordersCanadaHIV InfectionsHomosexuality, MaleHumansMaleMiddle AgedOptimismProspective StudiesYoung AdultMethamphetamineGay and bisexual menHIV/AIDSHIV treatment optimismMen who have sex with men (MSM)MethamphetamineTreatment as prevention (TasP)

Identifiers

PMID29427917
PMCPMC5889742

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.