Evidence map›Paper›PMID 29427808›Full record

ReviewCurrent opinion in neurobiology2018

Adaptive optical microscopy for neurobiology.

Cristina Rodríguez, Na Ji

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
10.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
  2. Light force-powered cellular medical micromachines.Frontiers in bioengineering and biotechnology · 2026
    Review
  3. Article
  4. Perspective: An outlook on fluorescence tracking.The Journal of chemical physics · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Adaptive optics for optical microscopy [Invited].Biomedical optics express · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Cristina RodríguezJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Na JiJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA; Department of Physics, Department of Molecular & Cellular Biology, University of California, Berkeley, CA 94720, USA. Electronic address: jina@berkeley.edu.
Howard Hughes Medical Institute · USUniversity of California, Berkeley · US

Funding

High-Speed Volumetric Imaging of Neural Activity throughout the Living Brain - Supplement RequestU01NS103489 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI JI, NA · 2017 to 2019
$2.7M
Calcium biosensors for deep-tissue imaging and spectral multiplexingU01NS103573 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI VERKHUSHA, VLADISLAV · 2017 to 2019
$1.8M
Howard Hughes Medical InstituteNINDS NIH HHS U01 NS103489NINDS NIH HHS U01 NS103573
6 · The paper itself

Abstract

With the ability to correct for the aberrations introduced by biological specimens, adaptive optics-a method originally developed for astronomical telescopes-has been applied to optical microscopy to recover diffraction-limited imaging performance deep within living tissue. In particular, this technology has been used to improve image quality and provide a more accurate characterization of both structure and function of neurons in a variety of living organisms. Among its many highlights, adaptive optical microscopy has made it possible to image large volumes with diffraction-limited resolution in zebrafish larval brains, to resolve dendritic spines over 600μm deep in the mouse brain, and to more accurately characterize the orientation tuning properties of thalamic boutons in the primary visual cortex of awake mice.

Indexed as

MicroscopyOptics and PhotonicsAnimalsBrainDendritesHumansLarvaNeurobiologyNeuronsZebrafish

Identifiers

PMID29427808
PMCPMC5984664
OpenAlexW2790768036

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.