Evidence map›Paper›PMID 29427739›Full record

ArticleJournal of pain and symptom management2018

Predictors of Late Palliative Care Referral in Children With Cancer.

Erica C Kaye, Jonathan Jerkins, Courtney A Gushue, Samantha DeMarsh, April Sykes, Zhaohua Lu, Jennifer M Snaman, Lindsay Blazin, Liza-Marie Johnson, Deena R Levine and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of pain and symptom management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Pediatric Oncology Hospice: A Comprehensive Review.The American journal of hospice & palliative care · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Racial and Ethnic Differences in Inpatient Palliative Care for Pediatric Stem Cell Transplant Patients.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2022
    Article
  15. Observational
  16. Article
  17. Article
  18. Review
  19. Relationship of race and ethnicity on access, timing, and disparities in pediatric palliative care for children with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Erica C KayeSt. Jude Children's Research Hospital, Memphis, Tennessee, USA. Electronic address: erica.kaye@stjude.org.
Jonathan JerkinsLe Bonheur Children's Hospital, Memphis, Tennessee, USA; University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Courtney A GushueNationwide Children's Hospital, Columbus, Ohio, USA.
Samantha DeMarshOhio University Heritage College of Osteopathic Medicine, Cleveland, Ohio, USA.
April SykesSt. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Zhaohua LuSt. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Jennifer M SnamanDana-Farber Cancer Institute, Boston, Massachusetts, USA; Boston Children's Hospital, Boston, Massachusetts, USA.
Lindsay BlazinSt. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Liza-Marie JohnsonSt. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Deena R LevineSt. Jude Children's Research Hospital, Memphis, Tennessee, USA.
R Ray MorrisonSt. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Justin N BakerSt. Jude Children's Research Hospital, Memphis, Tennessee, USA.
St. Jude Children's Research Hospital · USBoston Children's Hospital · USNationwide Children's Hospital · USOhio University · USUniversity of Tennessee Health Science Center · US

Funding

PROFESSIONAL ONCOLOGY EDUCATION PROGRAMR25CA023944 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI SUZANNE A. GRONEMEYER · 1986 to 2026
$8.3M
NCI NIH HHS R25 CA023944
6 · The paper itself

Abstract

contextEarly integration of palliative care (PC) in the management of children with high-risk cancer is widely endorsed by patients, families, clinicians, and national organizations. However, optimal timing for PC consultation is not standardized, and variables that influence timing of PC integration for children with cancer remain unknown.

objectivesTo investigate associations between demographic, disease, treatment, and end-of-life attributes and timing of PC consultation for children with high-risk cancer enrolled on a PC service.

methodsA comprehensive standardized tool was used to abstract data from the medical records of 321 patients treated at a large academic pediatric cancer center, who died between 2011 and 2015.

resultsGender, race, ethnicity, enrollment on a Phase I protocol, number of high-acuity hospitalizations, and receipt of cardiopulmonary resuscitation were not associated with timing of PC involvement. Patients with hematologic malignancy, those who received cancer-directed therapy during the last month of life, and those with advance directives documented one week or less before death had higher odds of late PC referral (malignancy: odds ratio [OR] 3.24, P = 0.001; therapy: OR 4.65, P < 0.001; directive: OR 4.81, P < 0.0001). Patients who received hospice services had lower odds of late PC referral <30 days before death (OR 0.31, P < 0.001).

conclusionHematologic malignancy, cancer-directed therapy at the end of life, and delayed documentation of advance directives are associated with late PC involvement in children who died of cancer. Identification of these variables affords opportunities to study targeted interventions to enhance access to earlier PC resources and services for children with high-risk cancer and their families.

Indexed as

Palliative CareReferral and ConsultationAdolescentChildChild, PreschoolFemaleHospice CareHumansMaleNeoplasmsPrognosisRetrospective StudiesTime-to-Treatmentconsultationearly integrationPalliative carepalliative oncologypediatric oncologytiming

Identifiers

PMID29427739
PMCPMC6223026
OpenAlexW2785379598

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.