ArticleJournal of the American Geriatrics Society2018
Chronic Physical Conditions, Multimorbidity, and Mild Cognitive Impairment in Low- and Middle-Income Countries.
Article in Journal of the American Geriatrics Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 6 of them syntheses that pooled it.
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Who cites it
73 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Impact of edentulism on community-dwelling adults in low-income, middle-income and high-income countries: a systematic review.BMJ open · 2024Pooled it
- Unclean Cooking Fuel Use and Slow Gait Speed Among Older Adults From 6 Countries.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Pooled it
- Pain and mild cognitive impairment among adults aged 50 years and above residing in low- and middle-income countries.Aging clinical and experimental research · 2023Pooled it
- Multimorbidity of non-communicable diseases in low-income and middle-income countries: a systematic review and meta-analysis.BMJ open · 2022Pooled it
- Patterns of multimorbidity and some psychiatric disorders: A systematic review of the literature.Frontiers in psychology · 2022Pooled it
- Prevalence of mild cognitive impairment in patients with hypertension: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Pooled it
- Functional autonomy, comorbidities and cognitive decline: a mediation analysis in neurocognitive disorders.Frontiers in aging neuroscience · 2026Article
- Article
- Observational
- The Egyptian Dementia Network (EDN): Baseline characteristics from the first dementia registry in an African Arab country.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- A Network Analysis of Food Intake and Cognitive Function in Older Adults with Multimorbidity: A National Cross-Sectional Study.Nutrients · 2025Article
- Multimorbidity in dementia: Current perspectives and future challenges.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Review
- Physical multimorbidity and dynapenic abdominal obesity among older adults from low- and middle-income countries.Communications medicine · 2025Article
- Association between dynapenic abdominal obesity and mild cognitive impairment among middle-aged and older community-dwelling adults.Aging clinical and experimental research · 2025Article
- Presence of chronic morbidities alters skeletal muscle health and amino acid kinetics in mild cognitive impairment.Journal of Alzheimer's disease : JAD · 2025Article
- Association Between Unclean Cooking Fuel Use and Hearing Problems Among Adults Aged ≥ 65 Years, a Cross-Sectional Study.Health science reports · 2025Article
- Assessment of Health System Readiness and Quality of Dementia Services in Peru: Protocol for a Qualitative Study With Stakeholder Interviews and Documentation Review.JMIR research protocols · 2025Article
- Fruit and vegetable consumption and injurious falls among adults aged ≥ 50 years from low- and middle-income countries.Aging clinical and experimental research · 2025Article
- Inequalities in Mild Cognitive Impairment Risk Among Chinese Middle-Aged and Older Adults: Insights from an Integrated Learning Model.Risk management and healthcare policy · 2025Article
- Rethinking and transforming health systems for dementia care in low- and middle-income country settings.PLOS global public health · 2025Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectivesTo assess the association between chronic physical conditions and multimorbidity and mild cognitive impairment (MCI) in low- and middle-income countries (LMICs).
designNationally representative, cross-sectional, community-based study.
settingSix countries that participated in the World Health Organization Study on Global Ageing and Adult Health.
participantsIndividuals aged 50 and older (N=32,715; mean age 62.1 ± 15.6; 51.7% female). MEASUREMENTS: The definition of MCI was based on the recommendations of the National Institute on Ageing and Alzheimer's Association. Ten chronic conditions were assessed (angina pectoris, arthritis, asthma, cataract, chronic lung disease, diabetes mellitus, edentulism, hearing problems, hypertension, stroke). Multivariable logistic regression analysis was conducted to assess the association between chronic physical conditions, multimorbidity (≥2 chronic conditions), and MCI.
resultsThe prevalence of multimorbidity was 49.8% (95% confidence interval (CI)=48.1-51.5%) and of MCI was 15.3% (95% CI=14.4-16.3%). After adjustment for potential confounders, edentulism (odds ratio (OR)=1.24), arthritis (OR=1.24), chronic lung disease (OR=1.29), cataract (OR=1.33), stroke (OR=1.94), hearing problems (OR=2.27), and multimorbidity (OR=1.40) were significantly associated with MCI. There was a gradual increase in the likelihood of MCI (1 condition: OR=1.21, 95% CI=1.03-1.42; ≥4 conditions: OR=2.07, 95% CI=1.70-2.52).
conclusionThese results highlight the need to investigate the underlying mechanisms linking chronic conditions and MCI and whether prevention or treatment of chronic conditions or multimorbidity can reduce the onset of cognitive decline and subsequent dementia, especially in LMICs.
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