Evidence map›Paper›PMID 29427503›Full record

ArticleJournal of the American Geriatrics Society2018

36-Item Short Form Survey (SF-36) Versus Gait Speed As Predictor of Preclinical Mobility Disability in Older Women: The Women's Health Initiative.

Deepika R Laddu, Betsy C Wertheim, David O Garcia, Nancy F Woods, Michael J LaMonte, Bertha Chen, Hoda Anton-Culver, Oleg Zaslavsky, Jane A Cauley, Rowan Chlebowski and 4 more

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Protein Intake and Functional Integrity in Aging: The Framingham Heart Study Offspring.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Deepika R LadduDepartment of Physical Therapy, University of Illinois at Chicago, Chicago, Illinois.ORCID 0000-0001-6790-0220
Betsy C WertheimUniversity of Arizona Cancer Center, Tucson, Arizona.
David O GarciaDepartment of Health Promotion Sciences, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona.
Nancy F WoodsSchool of Nursing, University of Washington, Seattle, Washington.
Michael J LaMonteDepartment of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo-State University of New York, Buffalo, New York.
Bertha ChenDepartment of Obstetrics and Gynecology, School of Medicine, Stanford University, Palo Alto, California.
Hoda Anton-CulverDepartment of Epidemiology, University of California, Irvine, Irvine, California.
Oleg ZaslavskySchool of Nursing, University of Washington, Seattle, Washington.
Jane A CauleyGraduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.
Rowan ChlebowskiLos Angeles Medical Center, Los Angeles Biomedical Research Institute at Harbor-University of California, Torrance, California.
JoAnn E MansonDivision of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Cynthia A ThomsonUniversity of Arizona Cancer Center, Tucson, Arizona.
Marcia L StefanickDepartment of Obstetrics and Gynecology, School of Medicine, Stanford University, Palo Alto, California.
Women's Health Initiative Investigators

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Justin M Snider · 1985 to 2026
$110.2M
NCI NIH HHS P30 CA023074NHLBI NIH HHS HHSN268201100001INHLBI NIH HHS HHSN268201100002INHLBI NIH HHS HHSN268201100003INHLBI NIH HHS HHSN268201100046CNIA NIH HHS HHSN271201100004CWHI NIH HHS HHSN268201100001CWHI NIH HHS HHSN268201100002CWHI NIH HHS HHSN268201100003CWHI NIH HHS HHSN268201100004C
6 · The paper itself

Abstract

objectivesTo compare the value of clinically measured gait speed with that of the self-reported Medical Outcomes Study 36-item Short-Form Survey Physical Function Index (SF-36 PF) in predicting future preclinical mobility disability (PCMD) in older women.

designProspective cohort study.

settingForty clinical centers in the United States.

participantsWomen aged 65 to 79 enrolled in the Women's Health Initiative Clinical Trials with gait speed and SF-36 assessed at baseline (1993-1998) and follow-up Years 1, 3, and 6 (N = 3,587). MEASUREMENTS: Women were categorized as nondecliners or decliners based on changes (from baseline to Year 1) in gait speed and SF-36 PF scores. Logistic regression models were used to estimate incident PCMD (gait speed <1.0 m/s) at Years 3 and 6. Area under the receiver operating characteristic curve (AUC) was used to compare the predictive value of SF-36 PF with that of measured gait speed.

resultsSlower baseline gait speed and lower SF-36 PF scores were associated with higher adjusted odds of PCMD at Years 3 and 6 (all P < .001). For gait speed, decliners were 2.59 times as likely to have developed PCMD as nondecliners by Year 3 and 2.35 times as likely by Year 6. Likewise, for SF-36, decliners were 1.42 times as likely to have developed PCMD by Year 3 and 1.49 times as likely by Year 6. Baseline gait speed (AUC = 0.713) was nonsignificantly better than SF-36 (AUC = 0.705) at predicting PCMD over 6 years (P = .21); including measures at a second time point significantly improved model discrimination for predicting PCMD (all P < .001).

conclusionGait speed identified PCMD risk in older women better than the SF-36 PF did, although the results may be limited given that gait speed served as a predictor and to define the PCMD outcome. Nonetheless, monitoring trajectories of change in mobility are better predictors of future mobility disability than single measures.

Indexed as

Mobility LimitationWomen's HealthAgedFemaleGaitGeriatric AssessmentHumansSelf ReportSurveys and QuestionnairesWalkingdisabilitygeriatric assessmentperformancephysical functionprevention

Identifiers

PMID29427503
PMCPMC5906155

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.