Evidence map›Paper›PMID 29427417›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Liping Hu, Weiqi Huang, Ling Bei, Larisa Broglie, Elizabeth A Eklund

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Normal Hematopoiesis Is a Balancing Act of Self-Renewal and Regeneration.Cold Spring Harbor perspectives in medicine · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Liping HuNorthwestern University, Chicago, IL 60611.
Weiqi HuangNorthwestern University, Chicago, IL 60611.ORCID 0000-0001-6779-6961
Ling BeiNorthwestern University, Chicago, IL 60611.
Larisa BroglieLurie Children's Hospital, Chicago, IL 60611.
Elizabeth A EklundNorthwestern University, Chicago, IL 60611; e-eklund@northwestern.edu.
Northwestern University · USLurie Children's Hospital · US

Funding

Triad1 regulates myelopoiesis and functions as a leukemia suppressorR01CA195642 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI EKLUND, ELIZABETH ANN · 2015 to 2019
$1.8M
The role of ICSBP in the pathogenesis of chronic myeloid leukemiaR01CA174205 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI EKLUND, ELIZABETH ANN · 2013 to 2017
$1.6M
Molecular mechanisms for bone marrow failure and clonal progression during the innate immune response in Fanconi AnemiaR01DK121354 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI EKLUND, ELIZABETH ANN · 2019 to 2022
$1.4M
The role of emergency granulopoiesis in the pathogenesis of Fanconi AnemiaR01DK098812 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI EKLUND, ELIZABETH ANN · 2014 to 2017
$1.3M
Molecular Mechanisms of Disease Progression in Myeloid MalignancyI01BX002067 · VA · JESSE BROWN VA MEDICAL CENTER · PI EKLUND, ELIZABETH ANN · 2013 to 2016
–
Identifying molecular markers that predict relapse after therapy discontinuation inchronic myeloid leukemia.I01CX001864 · VA · JESSE BROWN VA MEDICAL CENTER · PI Elizabeth Ann Eklund · 2019 to 2026
–
BLRD VA I01 BX002067CSRD VA I01 CX001864NCI NIH HHS R01 CA174205NCI NIH HHS R01 CA195642NIDDK NIH HHS R01 DK098812NIDDK NIH HHS R01 DK121354
6 · The paper itself

Abstract

Emergency (stress) granulopoiesis is an episodic process for the production of granulocytes in response to infectious challenge. We previously determined that Fanconi C, a component of the Fanconi DNA-repair pathway, is necessary for successful emergency granulopoiesis. Fanconi anemia results from mutation of any gene in this pathway and is characterized by bone marrow failure (BMF) in childhood and clonal progression in adolescence. Although murine Fanconi anemia models exhibit relatively normal steady-state hematopoiesis,

Indexed as

AnimalsApoptosisAtaxia Telangiectasia Mutated ProteinsBone MarrowDNA DamageDNA RepairFanconi AnemiaFanconi Anemia Complementation Group C ProteinGranulocytesHaploinsufficiencyLeukopoiesisMiceTumor Suppressor Protein p53Ataxia Telangiectasia Mutated ProteinsFancc protein, mouseFanconi Anemia Complementation Group C ProteinTrp53 protein, mouseTumor Suppressor Protein p53

Identifiers

PMID29427417
PMCPMC5834788
OpenAlexW2785752893

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.