Evidence map›Paper›PMID 29427206›Full record

ArticleDermatology and therapy2018

Neuromodulation in Inflammatory Skin Disease.

Eric J Yang, Sahil Sekhon, Kristen M Beck, Tina Bhutani, John Koo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Dermatology and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Alternative Psychotherapeutic Approaches to the Treatment of Eczema.Clinical, cosmetic and investigational dermatology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Eric J YangDepartment of Dermatology, University of California-San Francisco, San Francisco, CA, USA. ericjyang@outlook.com.
Sahil SekhonDepartment of Dermatology, University of California-San Francisco, San Francisco, CA, USA.
Kristen M BeckDepartment of Dermatology, University of California-San Francisco, San Francisco, CA, USA.
Tina BhutaniDepartment of Dermatology, University of California-San Francisco, San Francisco, CA, USA.
John KooDepartment of Dermatology, University of California-San Francisco, San Francisco, CA, USA.
University of California, San Francisco · USRosalind Franklin University of Medicine and Science · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory skin diseases are difficult to treat because of a lack of available treatment options for severe disease. However, recent advances have shown that vagus nerve stimulation can be used to decrease inflammation and reduce disease severity in rheumatoid arthritis and inflammatory bowel disease. Changes in cytokine profiles observed in these studies are similar to those seen with use of biologics in inflammatory skin disease, suggesting that they act along similar pathways to disrupt chronic inflammation and treat inflammatory disease. This commentary explores the existing evidence demonstrating the efficacy of neuromodulation in inflammatory disease, and outlines reasons why these findings could translate to the dermatology setting to treat inflammatory skin disease.

Indexed as

Autonomic imbalanceInflammationInflammatory skin diseaseNeuromodulationTreatmentVagus nerve stimulation

Identifiers

PMID29427206
PMCPMC5825332
OpenAlexW2791554688

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.