Evidence map›Paper›PMID 29427164›Full record

ArticleWorld journal of pediatrics : WJP2018

Plasma gelsolin level predicts acute kidney injury after cardiopulmonary bypass in infants and young children.

Shan-Shan Shi, Xiao-Jie Yue, Dong-Yan Zhao, Jia-Jie Fan, Jian-Guo Xu, Xi-Wang Liu, Bao-Li Cheng, Xiang-Ming Fang, Jie Fan, Qiang Shu

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in World journal of pediatrics : WJP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Gelsolin as a predictor of arteriovenous fistula maturation.Clinical and experimental nephrology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Shan-Shan ShiCardiac Intensive Care Unit, The Children's Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Xiao-Jie YueThe Key Laboratory for Diagnosis and Therapy of Neonatal Diseases, The Children's Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Dong-Yan ZhaoThe Key Laboratory for Diagnosis and Therapy of Neonatal Diseases, The Children's Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Jia-Jie FanCardiac Intensive Care Unit, The Children's Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Jian-Guo XuDepartment of Anesthesiology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Xi-Wang LiuDepartment of Thoracic and Cardiovascular Surgery, The Children's Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Bao-Li ChengDepartment of Anesthesiology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Xiang-Ming FangDepartment of Anesthesiology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Jie FanDepartment of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Qiang ShuDepartment of Thoracic and Cardiovascular Surgery, The Children's Hospital of Zhejiang University School of Medicine, Hangzhou, China. shuqiang@zju.edu.cn.
Children's Hospital of Zhejiang University · CNFirst Affiliated Hospital Zhejiang University · CNUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) after cardiopulmonary bypass (CPB) is a common complication especially in pediatric population. Plasma gelsolin (pGSN) is an anti-inflammatory factor through binding with actin and pro-inflammatory cytokines in circulation. Decrease in pGSN has been reported in some pathologic conditions. The purpose of the study was to determine the alterations of pGSN level in infants and young children after CPB and the role of pGSN as a predictor for the morbidity and severity of post-CPB AKI.

methodsSixty-seven infants and young children at age ≤ 3 years old undergoing CPB were prospectively enrolled. PGSN levels were measured during peri-operative period with enzyme-linked immuno-sorbent assay and normalized with plasma total protein concentration. Other clinical characteristics of the patients were also recorded.

resultsIn patients developing AKI, the normalized pGSN (pGSN

conclusionsDecreased pGSN

Indexed as

Acute Kidney InjuryAge FactorsBiomarkersCardiopulmonary BypassChild, PreschoolChinaCohort StudiesCreatinineFemaleGelsolinHumansInfantMalePredictive Value of TestsPrognosisProspective StudiesBiomarkersCreatinineGelsolinAcute kidney injuryCardiopulmonary bypassInfantsPlasma gelsolinYoung children

Identifiers

PMID29427164
OpenAlexW2792555823

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.