Evidence map›Paper›PMID 29427144›Full record

ArticleInternational urology and nephrology2018

Outcomes of synchronous and metachronous bilateral small renal masses (< 4 cm): a population-based cohort study.

Nissar Ahmed Sheikh, Mohammed Hassan Khan, Sanjay Pillai, Stephen Lang, Ghulam Nabi

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In one paragraph

Article in International urology and nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Article
  5. Active surveillance of small renal masses.Insights into imaging · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nissar Ahmed SheikhAcademic Urology Unit, Cancer Research Division, Department of Urology, School of Medicine, Ninewells Hospital, University of Dundee, Dundee, DD1 9SY, Scotland, UK.
Mohammed Hassan KhanAcademic Urology Unit, Cancer Research Division, Department of Urology, School of Medicine, Ninewells Hospital, University of Dundee, Dundee, DD1 9SY, Scotland, UK.
Sanjay PillaiAcademic Urology Unit, Cancer Research Division, Department of Urology, School of Medicine, Ninewells Hospital, University of Dundee, Dundee, DD1 9SY, Scotland, UK.
Stephen LangAcademic Urology Unit, Cancer Research Division, Department of Urology, School of Medicine, Ninewells Hospital, University of Dundee, Dundee, DD1 9SY, Scotland, UK.
Ghulam NabiAcademic Urology Unit, Cancer Research Division, Department of Urology, School of Medicine, Ninewells Hospital, University of Dundee, Dundee, DD1 9SY, Scotland, UK. g.nabi@dundee.ac.uk.
Ninewells Hospital · GBUniversity of Dundee · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo report longitudinal outcomes of a population-based cohort of patients diagnosed with bilateral small renal masses from a period of over 11 years. PATIENTS AND

methodsConsecutive patients diagnosed with bilateral small renal masses (synchronous or metachronous) of a defined geographical area were recorded in a large database (TUCAN database) between January 2005 and December 2016. Patients had a unique identifier number and followed during this period using an agreed upon protocol. Clinicopathological characteristics and outcomes of bilateral small renal masses on active surveillance were analysed and compared to propensity score-matched sporadic unilateral small renal masses. Data were analysed for renal mass growth rate, rate of intervention and development of metastatic disease and patient survival.

resultsA total of 1060 patients were diagnosed with renal cancer, of which bilateral small renal masses accounted for 70 (6.6%) cases. Synchronous SRMs were observed in 63 patients, whereas metachronous lesions were found in seven patients during the study period. Metachronous lesion mean time to appearance was 62 ± 41 months (range 9-149 months). While most cases were sporadic, four were found to be hereditary. Growth rate of bilateral small renal masses did not differ from that of unilateral sporadic small renal masses. Similarly, there were no differences between the groups for rate of interventions and survival.

conclusionsProgression, rate of metastases and survival for patients diagnosed with bilateral small renal masses are similar to those diagnosed with unilateral disease.

Indexed as

AgedDisease ProgressionFemaleHumansKidney NeoplasmsLongitudinal StudiesMaleMiddle AgedNeoplasm MetastasisNeoplasms, Multiple PrimaryNeoplasms, Second PrimaryNephrectomyOrgan Sparing TreatmentsPropensity ScoreSurvival RateTime FactorsActive surveillanceNephrectomyRenal cancerSurgery

Identifiers

PMID29427144
OpenAlexW2792906105

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.