GuidelinePediatric radiology2018
2017 PRETEXT: radiologic staging system for primary hepatic malignancies of childhood revised for the Paediatric Hepatic International Tumour Trial (PHITT).
Guideline in Pediatric radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
123 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evidence on Indications and Techniques to Increase the Future Liver Remnant in Children Undergoing Extended Hepatectomy: A Systematic Review and Meta-Analysis of Individual Patient Data.Frontiers in pediatrics · 2022Pooled it
- Challenges with the PRETEXT staging system: a SIOPEL Radiology Group position paper.Pediatric radiology · 2026Review
- Quantitative analysis of tumor perfusion via contrast-enhanced ultrasound to predict the neoadjuvant chemotherapy efficacy for children with hepatoblastoma.Journal of ultrasound · 2026Article
- Clinical Risk Factors and Outcomes of Spontaneous Hepatoblastoma Rupture in Children: A 10-Year Propensity Score-Matched Study.Journal of clinical medicine · 2026Article
- Prognostic prediction of hepatoblastoma in children: development and validation of machine learning models-an SEER-based study.Updates in surgery · 2026Article
- Open Questions in Surgery for Hepatoblastoma: A Joined SIOPEL-IPSO Survey.European journal of haematology · 2026Article
- Non-hepatoblastoma pediatric liver tumors: Unravelling of a lesser-known entity.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- Improving image quality and diagnostic confidence for PRETEXT staging in pediatric hepatoblastoma using thin-slice and low-energy virtual monochromatic images in dual-energy CT with deep learning image reconstruction algorithm.BMC medical imaging · 2026Article
- Imaging and characterization of pulmonary nodules in children with solid tumors: what makes a pulmonary nodule a metastasis?Pediatric radiology · 2026Review
- Landscape of Somatic Alterations in Thai Pediatric Hepatoblastoma: Implications for Clinical Outcomes and Therapeutic Opportunities.Medicina (Kaunas, Lithuania) · 2026Article
- Comment on: "Surgical resection of giant hepatoblastoma involving second and third hepatic portals" by Zhen et al.Pediatric surgery international · 2026Article
- Pediatric Hepatoblastoma: From Developmental Molecular Mechanisms to Innovative Therapeutic Strategies.Cancers · 2026Review
- Magnetic resonance imaging-based deep-learning radiomics score for survival prediction and risk stratification in pediatric hepatoblastoma receiving surgical resection.World journal of radiology · 2026Article
- Treatment and outcomes of hepatoblastoma in a tertiary care pediatric institution: a single-center experience.Frontiers in oncology · 2026Article
- Pathology reporting of hepatoblastoma resections: recommendations from the international collaboration on cancer reporting.Histopathology · 2025Review
- Patient-specific virtual surgical simulation: the preliminary exploration of surgical evaluation for difficult pediatric liver tumors.BMC surgery · 2025Article
- Outcomes of major liver resection for children with hepatoblastoma weighing less than 10 kg: avoiding liver transplantation with extended or extreme resection.Pediatric surgery international · 2025Article
- White paper on the current state of imaging biomarkers in paediatric oncology.Pediatric radiology · 2025Review
- Prognostic Value of POST-Treatment Extent of Tumor (POSTTEXT) System in Patients with Hepatoblastoma.Cancer research and treatment · 2025Article
- Implementation of Comprehensive Surgical Guidelines for Hepatoblastoma: Analysis of the Children's Oncology Group AHEP0731 Phase III Trial.Annals of surgery · 2025Article
63 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Imaging is crucial in the assessment of children with a primary hepatic malignancy. Since its inception in 1992, the PRETEXT (PRE-Treatment EXTent of tumor) system has become the primary method of risk stratification for hepatoblastoma and pediatric hepatocellular carcinoma in numerous cooperative group trials across the world. The PRETEXT system is made of two components: the PRETEXT group and the annotation factors. The PRETEXT group describes the extent of tumor within the liver while the annotation factors help to describe associated features such as vascular involvement (either portal vein or hepatic vein/inferior vena cava), extrahepatic disease, multifocality, tumor rupture and metastatic disease (to both the lungs and lymph nodes). This manuscript is written by members of the Children's Oncology Group (COG) in North America, the International Childhood Liver Tumors Strategy Group (SIOPEL) in Europe, and the Japanese Study Group for Pediatric Liver Tumor (JPLT; now part of the Japan Children's Cancer Group) and represents an international consensus update to the 2005 PRETEXT definitions. These definitions will be used in the forthcoming Trial to Pediatric Hepatic International Tumor Trial (PHITT).
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.