Evidence map›Paper›PMID 29426990›Full record

ArticleEuropean radiology2018

What are the predictors of clinical success after percutaneous vertebroplasty for osteoporotic vertebral fractures?

Elsa Denoix, Flore Viry, Agnes Ostertag, Caroline Parlier-Cuau, Jean-Denis Laredo, Martine Cohen-Solal, Valérie Bousson, Thomas Funck-Brentano

Abstract read
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In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Incidence and predictors of residual back pain after percutaneous vertebral augmentation in osteoporotic vertebral compression fracture: a systematic review and meta analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Pooled it
  2. Article
  3. Article
  4. Lumbar muscle involvement in the occurrence of osteoporotic vertebral fracture.Research in diagnostic and interventional imaging · 2024
    Article
  5. Article
  6. Review
  7. [Clinical study of percutaneous vertebroplasty through extreme extrapedicular approach in the treatment of osteoporotic vertebral compression fracture].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2019
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Elsa DenoixDepartment of Rheumatology, AP-HP, Lariboisière Teaching Hospital, F-75475, Paris, France.
Flore ViryDepartment of Musculoskeletal Radiology, AP-HP, Lariboisière Teaching Hospital, F-75475, Paris, France.
Agnes OstertagBIOSCAR UMRS 1132, Université Paris Diderot, Sorbonne Paris Cité, INSERM, F-75475, Paris, France.
Caroline Parlier-CuauDepartment of Musculoskeletal Radiology, AP-HP, Lariboisière Teaching Hospital, F-75475, Paris, France.
Jean-Denis LaredoDepartment of Musculoskeletal Radiology, AP-HP, Lariboisière Teaching Hospital, F-75475, Paris, France.
Martine Cohen-SolalDepartment of Rheumatology, AP-HP, Lariboisière Teaching Hospital, F-75475, Paris, France.
Valérie BoussonDepartment of Musculoskeletal Radiology, AP-HP, Lariboisière Teaching Hospital, F-75475, Paris, France.
Thomas Funck-BrentanoDepartment of Rheumatology, AP-HP, Lariboisière Teaching Hospital, F-75475, Paris, France. thomas.funck-brentano@aphp.fr.ORCID http://orcid.org/0000-0001-7684-2405
Assistance Publique – Hôpitaux de Paris · FRInserm · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOsteoporotic vertebral fractures are responsible for acute pain and disability that may persist for more than 2 months. We wanted to identify predicting factors for mid-term outcome after vertebroplasty.

methodsWe included consecutive patients who underwent vertebroplasty for fragility fractures with persistent and intense pain between January 2014-June 2016. Outcome was assessed by an independent clinician after 1 month using a standardized questionnaire. Patients were classified as having either a favorable or a poor outcome. Presence of an intravertebral cleft and bone oedema mean signal intensity was assessed by an independent radiologist blinded to the clinical data. Pre-intervention clinical or radiological factors were analysed as predictors for outcome.

resultsIn the 78 included patients (females 71%, age 75 ± 8.3 years), 61.5% had a favourable outcome. When vertebroplasty was performed within 2 months after fracture, the outcome was favourable in 19 patients (39.6%) and poor in five (16.7%; estimate for favourable outcome: OR = 4.1, 95% CI 1.2-13.8, p = 0.021). Absence of intravertebral cleft on pre-intervention imaging was also a predictor of favourable outcome (OR = 3.7, 95% CI 1.2-11.8, p = 0.024). On pre-intervention MRI, vertebral body oedema intensity signal did not influence the outcome.

conclusionsIn patients with persistent and intense pain after an osteoporotic vertebral fracture, early intervention and absence of intravertebral cleft were predictors of favourable outcome at 1 month after vertebroplasty. KEY POINTS: • Performing vertebroplasty within 2 months following a fragility fracture increases success rate. • Presence of an intravertebral cleft at baseline is a predictor of poor mid-term outcome. • A pre-intervention MRI should be performed to ascertain the indication of vertebroplasty.

Indexed as

AgedAged, 80 and overBone CementsFemaleFractures, CompressionHumansMagnetic Resonance ImagingMaleMiddle AgedOsteoporotic FracturesPain MeasurementPrognosisRadiographySpinal FracturesSurveys and QuestionnairesTomography, X-Ray ComputedBone CementsFractures, compressionOsteoporotic fracturesPain measurementTreatment outcomeVertebroplasty

Identifiers

PMID29426990
OpenAlexW2793190523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.