Evidence map›Paper›PMID 29426930›Full record

ArticleEuropean journal of clinical nutrition2018

Low diet quality and the risk of stroke mortality: the multiethnic cohort study.

Annette Aigner, Heiko Becher, Simone Jacobs, Lynne R Wilkens, Carol J Boushey, Loic Le Marchand, Christopher A Haiman, Gertraud Maskarinec

Open access · greenAbstract read
In one paragraph

Article in European journal of clinical nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 6 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 6 syntheses or guidelines pooled it, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Annette AignerInstitute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. a.aigner@uke.de.
Heiko BecherInstitute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Simone JacobsInstitute of Public Health, University of Heidelberg, Heidelberg, Germany.
Lynne R WilkensCancer Epidemiology, University of Hawaii Cancer Center, Honolulu, HI, USA.
Carol J BousheyCancer Epidemiology, University of Hawaii Cancer Center, Honolulu, HI, USA.
Loic Le MarchandCancer Epidemiology, University of Hawaii Cancer Center, Honolulu, HI, USA.
Christopher A HaimanDepartment of Preventive Medicine, Norris Cancer Center, University of Southern California, Los Angeles, CA, USA.
Gertraud MaskarinecCancer Epidemiology, University of Hawaii Cancer Center, Honolulu, HI, USA.
University of Hawaii System · USCancer Center of Hawaii · USUniversität Hamburg · DEUniversity Medical Center Hamburg-Eppendorf · DEUSC Norris Comprehensive Cancer Center · US

Funding

University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI Xin Chen · 1996 to 2026
$56.2M
Understanding Population Differences in Cancer: The MEC StudyU01CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2015 to 2025
$37.4M
NCI NIH HHS P30 CA071789NCI NIH HHS U01 CA164973
6 · The paper itself

Abstract

BACKGROUND/

objectivesSeveral diets, e.g., those low in fruits/vegetables, high in sodium, and red/processed meat, have been related to a higher stroke risk. We investigated stroke mortality associated with a priori diet-quality indices in the Multiethnic Cohort study. SUBJECTS/

methodsBased on 172,043 observations including 3548 stroke deaths, we investigated the Healthy Eating Index-2010 (HEI-2010), the Alternative HEI-2010, the alternate Mediterranean diet score, and the Dietary Approaches to Stop Hypertension index in relation to stroke mortality. Using Cox regression, we estimated adjusted population attributable risks (PAR) and hazard ratios (HR) for tertiles of the indices while adjusting for relevant confounders.

resultsThe associations between all diet-quality indices and stroke mortality were consistent in direction; a low-quality diet was associated with a greater risk of stroke death, but the HEI-2010 was the strongest predictor. The PAR for stroke death based on HEI-2010 was 7.9% (95%-CI: 3.7-12.2%), indicating the preventable percentage of deaths if the total population had the same diet quality as those in the highest tertile for this diet-quality index. The lowest as compared to the highest tertile of the HEI-2010 was associated with a 1.23-fold (95%-CI: 1.13-1.34) risk. The PARs for low and medium adherence to the indices were similar by sex and follow-up time, but varied by ethnicity, with the highest PAR in Whites (15.4%) and no association in Latinos.

conclusionsFindings for four diet-quality indices, in particular the HEI-2010, indicated that diet quality acts as an independent risk factor for stroke mortality. Promotion of a high diet quality could have a substantial impact on the prevention of stroke deaths.

Indexed as

DietEthnicityFeeding BehaviorAgedFemaleHispanic or LatinoHumansMaleMiddle AgedProportional Hazards ModelsProspective StudiesRisk FactorsStrokeWhite People

Identifiers

PMID29426930
PMCPMC6555553
OpenAlexW2791965973

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.