Evidence map›Paper›PMID 29426924›Full record

ArticleScientific reports2018

A biopotential optrode array: operation principles and simulations.

Amr Al Abed, Hrishikesh Srinivas, Josiah Firth, François Ladouceur, Nigel H Lovell, Leonardo Silvestri

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amr Al AbedGraduate School of Biomedical Engineering, UNSW, Sydney, 2052, Australia. amra@unsw.edu.au.
Hrishikesh SrinivasGraduate School of Biomedical Engineering, UNSW, Sydney, 2052, Australia.
Josiah FirthSchool of Electrical Engineering and Telecommunications, UNSW, Sydney, 2052, Australia.ORCID 0000-0003-1865-6617
François LadouceurSchool of Electrical Engineering and Telecommunications, UNSW, Sydney, 2052, Australia.
Nigel H LovellGraduate School of Biomedical Engineering, UNSW, Sydney, 2052, Australia.
Leonardo SilvestriGraduate School of Biomedical Engineering, UNSW, Sydney, 2052, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We propose an optical electrode 'optrode' sensor array for biopotential measurements. The transduction mechanism is based on deformed helix ferroelectric liquid crystals which realign, altering the optrode's light reflectance properties, relative to applied potential fields of biological cells and tissue. A computational model of extracellular potential recording by the optrode including the electro-optical transduction mechanism is presented, using a combination of time-domain and frequency-domain finite element analysis. Simulations indicate that the device has appropriate temporal response to faithfully transduce neuronal spikes, and spatial resolution to capture impulse propagation along a single neuron. These simulations contribute to the development of multi-channel optrode arrays for spatio-temporal mapping of electric events in excitable biological tissue.

Identifiers

PMID29426924
PMCPMC5807498

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.