Evidence map›Paper›PMID 29426908›Full record

ArticleCell death & disease2018

Temozolomide-perillyl alcohol conjugate downregulates O

Xingguo Song, Li Xie, Minghui Chang, Xinran Geng, Xingwu Wang, Thomas C Chen, Xianrang Song

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell death & disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. NEO212 induces mitochondrial apoptosis and impairs autophagy flux in ovarian cancer.Journal of experimental & clinical cancer research : CR · 2019
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Xingguo SongShandong Provincial Key Laboratory of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Li XieShandong Provincial Key Laboratory of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Minghui ChangDepartment of Clinical Laboratory, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Xinran GengMaternity & Child Care Center of Dezhou, Dongdizhong Street 835#, Decheng District, Dezhou, Shandong, China.
Xingwu WangShandong Provincial Key Laboratory of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Thomas C ChenDepartments of Neurological Surgery and Pathology, University of Southern California, Los Angeles, CA, USA.
Xianrang SongShandong Provincial Key Laboratory of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong, China. basiclab@163.com.ORCID 0000-0003-1722-8207
Shandong University · CNFuzhou Maternity and Child Health Care Hospital · CNUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The DNA repair enzyme O

Indexed as

A549 CellsAntineoplastic Agents, AlkylatingCarcinoma, Non-Small-Cell LungCell Line, TumorDNA Modification MethylasesDNA Repair EnzymesDown-RegulationHumansLung NeoplasmsMonoterpenesProteasome Endopeptidase ComplexTemozolomideTumor Suppressor ProteinsUbiquitinationAntineoplastic Agents, AlkylatingDNA Modification MethylasesDNA Repair EnzymesMGMT protein, humanMonoterpenesperillyl alcoholProteasome Endopeptidase ComplexTemozolomideTumor Suppressor Proteins

Identifiers

PMID29426908
PMCPMC5833843
OpenAlexW2790965864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.