ArticleScientific reports2018
Identification of basic/helix-loop-helix transcription factors reveals candidate genes involved in anthocyanin biosynthesis from the strawberry white-flesh mutant.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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34 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Pooled it
- Comprehensive analysis of bHLH transcription factors reveals candidate regulators of flower development and heat stress response in Rhododendron simsii.BMC plant biology · 2025Article
- Recent advances in biosynthesis and regulation of strawberry anthocyanins.Horticulture research · 2025Article
- The candidate gene SibHLHA regulates anthocyanin-driven purple pigmentation in Sesamum indicum flowers.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- GAPDH Gene Family inInternational journal of molecular sciences · 2025Article
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- Overexpression of PavHIPP16 from Prunus avium enhances cold stress tolerance in transgenic tobacco.BMC plant biology · 2024Article
- Deciphering the genetic architecture of fruit color in strawberry.Journal of experimental botany · 2023Review
- Transcriptomic analysis reveals the mechanism underlying the anthocyanin changes in Fragaria nilgerrensis Schlecht. and its interspecific hybrids.BMC plant biology · 2023Article
- Genome-wide identification of bHLH transcription factors and their response to salt stress inFrontiers in plant science · 2023Article
- Genome-Wide Analysis of the ERF Family and Identification of Potential Genes Involved in Fruit Ripening in Octoploid Strawberry.International journal of molecular sciences · 2022Article
- The genomic and bulked segregant analysis ofaBIOTECH · 2022Article
- Overexpression ofInternational journal of molecular sciences · 2022Article
- A Comprehensive Study of the WRKY Transcription Factor Family in Strawberry.Plants (Basel, Switzerland) · 2022Article
- Identification and Expression Analysis of Calcium-Dependent Protein Kinases Gene Family in Potato Under Drought Stress.Frontiers in genetics · 2022Article
- Transcriptome Analysis of MYB Genes and Patterns of Anthocyanin Accumulation During Seed Development in Wheat.Evolutionary bioinformatics online · 2022Article
- Insights into transcription factors controlling strawberry fruit development and ripening.Frontiers in plant science · 2022Review
- Comprehensive identification ofFrontiers in plant science · 2022Article
- Genome-Wide Identification and Characterization of MelonPlants (Basel, Switzerland) · 2021Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As the second largest transcription factor family in plant, the basic helix-loop-helix (bHLH) transcription factor family, characterized by the conserved bHLH domain, plays a central regulatory role in many biological process. However, the bHLH transcription factor family of strawberry has not been systematically identified, especially for the anthocyanin biosynthesis. Here, we identified a total of 113 bHLH transcription factors and described their chromosomal distribution and bioinformatics for the diploid woodland strawberry Fragaria vesca. In addition, transcription profiles of 113 orthologous bHLH genes from various tissues were analyzed for the cultivar 'Benihoppe', its white-flesh mutant 'Xiaobai', and the 'Snow Princess' from their fruit development to the ripening, as well as those under either the ABA or Eth treatment. Both the RT-PCR and qRT-PCR results show that seven selected FabHLH genes (FabHLH17, FabHLH25, FabHLH27, FabHLH29, FabHLH40, FabHLH80, FabHLH98) are responsive to the fruit anthocyanin biosynthesis and hormone signaling according to transcript profiles where three color modes are observed for strawberry's fruit skin and flesh. Further, prediction for the protein interaction network reveals that four bHLHs (FabHLH25, FabHLH29, FabHLH80, FabHLH98) are involved in the fruit anthocyanin biosynthesis and hormone signaling transduction. These bioinformatics and expression profiles provide a good basis for a further investigation of strawberry bHLH genes.
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