Evidence map›Paper›PMID 29426889›Full record

ArticleScientific reports2018

SiO

C Distasi, F A Ruffinatti, M Dionisi, S Antoniotti, A Gilardino, G Croci, B Riva, E Bassino, G Alberto, E Castroflorio and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

C DistasiDepartment of Pharmaceutical Sciences, University of Piemonte Orientale "A. Avogadro", Novara, Italy. carla.distasi@uniupo.it.
F A RuffinattiDepartment of Pharmaceutical Sciences, University of Piemonte Orientale "A. Avogadro", Novara, Italy.
M DionisiDepartment of Pharmaceutical Sciences, University of Piemonte Orientale "A. Avogadro", Novara, Italy.
S AntoniottiDepartment of Life Sciences and Systems Biology, University of Torino, Torino, Italy.
A GilardinoDepartment of Life Sciences and Systems Biology, University of Torino, Torino, Italy.
G CrociDepartment of Life Sciences and Systems Biology, University of Torino, Torino, Italy.
B RivaDepartment of Pharmaceutical Sciences, University of Piemonte Orientale "A. Avogadro", Novara, Italy.
E BassinoDepartment of Life Sciences and Systems Biology, University of Torino, Torino, Italy.
G AlbertoDepartment of Chemistry, University of Torino, Torino, Italy.
E CastroflorioCenter for Synaptic Neuroscience, Istituto Italiano di Tecnologia, Genova, Italy.
D IncarnatoDepartment of Life Sciences and Systems Biology, University of Torino, Torino, Italy.
E MorandiDepartment of Life Sciences and Systems Biology, University of Torino, Torino, Italy.
G MartraDepartment of Chemistry, University of Torino, Torino, Italy.ORCID 0000-0002-8012-5342
S OlivieroDepartment of Life Sciences and Systems Biology, University of Torino, Torino, Italy.
L MunaronDepartment of Life Sciences and Systems Biology, University of Torino, Torino, Italy.ORCID 0000-0001-9247-4446
D LovisoloDepartment of Life Sciences and Systems Biology, University of Torino, Torino, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Engineered silica nanoparticles (NPs) have attracted increasing interest in several applications, and particularly in the field of nanomedicine, thanks to the high biocompatibility of this material. For their optimal and controlled use, the understanding of the mechanisms elicited by their interaction with the biological target is a prerequisite, especially when dealing with cells particularly vulnerable to environmental stimuli like neurons. Here we have combined different electrophysiological approaches (both at the single cell and at the population level) with a genomic screening in order to analyze, in GT1-7 neuroendocrine cells, the impact of SiO

Indexed as

NanoparticlesAction PotentialsAnimalsCell LineGene ExpressionHypothalamusMiceNeuroendocrine CellsNeuronsSilicon DioxideSilicon Dioxide

Identifiers

PMID29426889
PMCPMC5807366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.