Evidence map›Paper›PMID 29426850›Full record

ArticleScientific reports2018

Asymmetrical ligand-induced cross-regulation of chemokine (C-X-C motif) receptor 4 by α

Xianlong Gao, Lauren J Albee, Brian F Volkman, Vadim Gaponenko, Matthias Majetschak

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. GPCR Heterodimers: Implications for Biased Signaling.Handbook of experimental pharmacology · 2026
    Review
  2. Activation of Chemokine (C-C Motif) Receptor 1 Modulates αJournal of the American Heart Association · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. αPharmacological research · 2023
    Article
  7. Review
  8. Article
  9. Heteromerization between αFEBS letters · 2022
    Article
  10. αProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Xianlong GaoBurn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, 60153, USA.
Lauren J AlbeeBurn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, 60153, USA.
Brian F VolkmanDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin, 53226, USA.
Vadim GaponenkoDepartment of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois, 60607, USA.
Matthias MajetschakBurn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, 60153, USA. mmajetschak@luc.edu.ORCID 0000-0002-4086-0887
Loyola University Chicago · USMedical College of Wisconsin · USUniversity of Illinois Chicago · US

Funding

Structural Basis for Chemokine FunctionR01AI058072 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI VOLKMAN, BRIAN F · 2004 to 2019
$4.1M
Structural Basis for Chemokine FunctionR37AI058072 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI Brian F Volkman · 2020 to 2026
$2.8M
Regulation of tyrosine kinase signaling through interaction with membrane lipidsR01CA188427 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI GAPONENKO, VADIM V, TYNER, ANGELA L · 2015 to 2019
$2.1M
Chemokine control of cardiovascular function during hemorrhagic shockR01GM107495 · NIGMS · UNIVERSITY OF SOUTH FLORIDA · PI MAJETSCHAK, MATTHIAS · 2014 to 2017
$1.1M
NCI NIH HHS R01 CA188427NIAID NIH HHS R01 AI058072NIAID NIH HHS R37 AI058072NIGMS NIH HHS R01 GM107495
6 · The paper itself

Abstract

Recently, we reported that chemokine (C-X-C motif) receptor (CXCR)4 and atypical chemokine receptor 3 regulate α

Indexed as

ChemotaxisAdrenergic alpha-1 Receptor Agonistsbeta-ArrestinsCell MembraneCells, CulturedHumansLigandsMyocytes, Smooth MusclePhenylephrineProtein BindingReceptors, Adrenergic, alpha-1Receptors, CXCR4Signal TransductionAdrenergic alpha-1 Receptor Agonistsbeta-ArrestinsCXCR4 protein, humanLigandsPhenylephrineReceptors, Adrenergic, alpha-1Receptors, CXCR4

Identifiers

PMID29426850
PMCPMC5807542
OpenAlexW2807433647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.