Evidence map›Paper›PMID 29426671›Full record

ArticleBrain stimulation

Decreased short-interval intracortical inhibition correlates with better pinch strength in patients with stroke and good motor recovery.

Karina Nocelo Ferreiro de Andrade, Adriana Bastos Conforto

Abstract read
In one paragraph

Article in Brain stimulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Karina Nocelo Ferreiro de AndradeNeurostimulation Laboratory, Neurology Clinical Division, Hospital das Clínicas/São Paulo University and Fundação Faculdade de Medicina, São Paulo, Brazil; NAPNA-USP (Núcleo de Apoio à Pequisa em Neurociência Aplicada), São Paulo University, São Paulo, Brazil. Electronic address: karinanoc@usp.br.
Adriana Bastos ConfortoNeurostimulation Laboratory, Neurology Clinical Division, Hospital das Clínicas/São Paulo University and Fundação Faculdade de Medicina, São Paulo, Brazil; NAPNA-USP (Núcleo de Apoio à Pequisa em Neurociência Aplicada), São Paulo University, São Paulo, Brazil; Hospital Israelita Albert Einstein, São Paulo, Brazil.

Funding

Nerve Stimulation to Improve Hand Weakness in StrokeR21TW006706 · FIC · UNIVERSITY OF SAO PAULO · PI CONFORTO, ADRIANA B · 2004 to 2004
$81k
FIC NIH HHS R21 TW006706
6 · The paper itself

Abstract

backgroundDeeper short-interval intracortical inhibition (SICI), a marker of GABA

objectivesWe evaluated the correlation between SICI in the affected hemisphere and pinch force of the paretic hand in well-recovered patients. We also investigated the correlation between SICI and pinch force in controls.

methodsTwenty-two subjects were included in the study. SICI was measured with a paired-pulse paradigm. The correlation between lateral pinch strength and SICI was assessed with Spearman's rho.

resultsThere was a significant correlation (rho = 0.69, p = 0.014) between SICI and pinch strength in patients, but not in controls. SICI was significantly deeper in patients with greater hand weakness.

conclusionsThese preliminary findings suggest that decreased GABA

Indexed as

AdultAgedEvoked Potentials, MotorFemaleHandHumansMaleMiddle AgedMotor CortexNeural InhibitionPinch StrengthRecovery of FunctionStrokeStroke RehabilitationTranscranial Magnetic StimulationChronic strokeIntracortical inhibitionRehabilitationTranscranial magnetic stimulation

Identifiers

PMID29426671
PMCPMC6019556

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.